MeCP2 Antibody (D-12): sc-137071
- MeCP2 Antibody (D-12) is a mouse monoclonal IgM κ provided at 200 µg/ml
- raised against amino acids 187-486 mapping near the C-terminus of MeCP2 of human origin
- recommended for detection of MeCP2 of human origin by WB, IP, IF and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for MeCP2 Antibody (D-12). This work is in progress.
QUICK LINKS
SEE ALSO...
MeCP2 Antibody (D-12) is a mouse monoclonal IgM antibody that detects MeCP2 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). MeCP2 plays a crucial role in the regulation of gene expression by binding to methylated DNA, particularly at methyl-CpG sites, which are often found in gene promoters. This binding is essential for maintaining the silencing of genes that should not be expressed in certain cell types, thereby contributing to cellular identity and function. Mutations in MeCP2 are linked to severe neurological disorders, including Rett syndrome, highlighting MeCP2′s importance in neuronal development and function. Anti-MeCP2 antibody (D-12) is particularly valuable for researchers studying the epigenetic regulation of gene expression and the molecular mechanisms underlying neurodevelopmental disorders, as MeCP2 (D-12) antibody allows for the visualization and quantification of MeCP2 in various experimental contexts.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MeCP2 Antibody (D-12) | sc-137071 | 200 µg/ml | $322.00 |