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MBLAC2 (metallo-beta-lactamase domain-containing protein 2), also known as beta-lactamase-like, is a 279 amino acid protein that belongs to the glyoxalase II family and metallo-beta-lactamase superfamily. Existing as two alternatively spliced isoforms, MBLAC2 binds two zinc ions and is encoded by a gene that maps to human chromosome 5q14.3. Chromosome 5 contains 181 million base pairs and comprises nearly 6% of the human genome. Chromosome 5 is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5-associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
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Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps MBLAC2 (A-4) | sc-398284 | 200 µg/ml | $316.00 | |||
MBLAC2 (A-4): m-IgG Fc BP-HRP Kit | sc-538411 | 200 µg Ab; 10 µg BP | $354.00 | |||
MBLAC2 (A-4): m-IgGκ BP-HRP Kit | sc-536020 | 200 µg Ab; 40 µg BP | $354.00 | |||
MBLAC2 (A-4): m-IgG1 BP-HRP Kit | sc-545691 | 200 µg Ab; 20 µg BP | $354.00 | |||
MBLAC2 (A-4) peptide neutralisant | sc-398284 P | 100 µg/0.5 ml | $68.00 |