Methionine adenosyltransferase (MAT) catalyzes the formation of S-adenosyltransferase (AdoMet) for methionine catabolism in the liver. MAT IIβ (methionine adenosyltransferase II, beta), also known as TGR, MAT-II or SDR23E1, is a 334 amino acid protein that is widely expressed and plays an important role in amino acid biosynthesis. Existing as a heterotetramer with two MAT IIα subunits, MAT IIβ functions as a non-catalytic regulatory protein that mediates the activity of MAT IIα, specifically by changing the kinetic properties of MAT IIα, thereby rendering it more susceptible to inhibition. MAT IIβ is expressed in hepatoma cells and is thought to play a role in cell proliferation, possibly by increasing the rate of DNA synthesis. Multiple isoforms of MAT IIβ exist due to alternative splicing events.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps MAT IIβ (H-4) | sc-514069 | 200 µg/ml | $316.00 | |||
MAT IIβ (H-4): m-IgG Fc BP-HRP Kit | sc-538580 | 200 µg Ab; 10 µg BP | $354.00 | |||
MAT IIβ (H-4): m-IgGκ BP-HRP Kit | sc-536218 | 200 µg Ab; 40 µg BP | $354.00 | |||
MAT IIβ (H-4): m-IgG1 BP-HRP Kit | sc-545779 | 200 µg Ab; 20 µg BP | $354.00 |