ACCÈS RAPIDE AUX LIENS
Misfolded glycoproteins are deglycosylated by the peptide N-glycanase during the degradation process. Free oligosaccharides released by N-glycanase are catabolized by cytosolic MAN2C1, also designated α-mannosidase 2C1. MAN2C1, a member of the glycosyl hydrolase 38 family, can cleave α 1,2-linked, α 1,3-linked and α 1,6-linked mannose residues and is stimulated by cobalt. The furanose analogs, swainsonine (SW) and 1,4-dideoxy-1,4-imino-d-mannitol (DIM), are known inhibitors of MAN2C1. The inhibition of MAN2C1 can enhance the adhesion of Jurkat T cells, showing a cytoskeletal rearrangement of the cells.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps MAN2C1 (G-8) | sc-271088 | 200 µg/ml | $316.00 | |||
MAN2C1 (G-8): m-IgG Fc BP-HRP Kit | sc-540198 | 200 µg Ab; 10 µg BP | $354.00 | |||
MAN2C1 (G-8): m-IgG1 BP-HRP Kit | sc-541965 | 200 µg Ab; 20 µg BP | $354.00 | |||
MAN2C1 (G-8) peptide neutralisant | sc-271088 P | 100 µg/0.5 ml | $68.00 |