Anticorps LXR beta/NER/NR1H2 (H-8): sc-133221
- L'Anticorps LXR beta/NER/NR1H2 (H-8) est un monoclonal de souris IgG1 κ, cité dans 4 publications, fourni en 200 µg/ml
- spécifique d'un épitope situé entre les acides aminés 42-81 près de N-terminus de LXRβ d'origine human
- recommandé pour la détection de LXRβ d'origine human par WB, IP, IF et ELISA
- Réactifs TransCruz pour une application en ChIP (sc-133221 X, 200 µg/0.1 ml)
- Voir LXR alpha/beta/NR1H3/NR1H2 (H-7): sc-377260 pour d'autres anticorps conjugués LXR beta/NER/NR1H2, dont AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 et 790.
- m-IgG Fc BP-HRP et 1 BP-HRP">m-IgG1 BP-HRP sont les réactifs de détection secondaire préférés pour LXR beta/NER/NR1H2 Antibody (H-8) for WB applications. Ces réactifs sont désormais proposés en lots avec LXR beta/NER/NR1H2 Antibody (H-8)(voir les informations de commande ci-dessous).
Retinoids are metabolites of vitamin A (retinol) and are believed to represent important signaling molecules during vertebrate development and tissue differentiation. The cooperation of liver X receptors (LXRs) α and β and retinoic X receptor (RXR) modulate the expression of several genes involved in lipid metabolism in hepatocyte and macrophages. RXR is the receptor for 9-cis retinoic acid and dimerizes with VDR, TR, PPAR and several novel receptors including liver X receptors LXRα (also referred to as RLD-1), LXRβ and FXR. FXR and LXR fall into a category of proteins termed "orphan receptors" because of their lack of a defined function, and in the case of LXR, the lack of a defined ligand. Both LXR/ RXR and FXR/RXR heterodimers retain their responsiveness to 9-cis retinoic acid. LXRα and LXRβ share considerable sequence homology and several functions, respond to the same endogenous and synthetic ligands and play critical roles in maintaining lipid homeostasis. LXRβ is ubiquitously expressed and enriched in tissues of neuronal and endocrine origin.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps LXR beta/NER/NR1H2 (H-8) | sc-133221 | 200 µg/ml | $316.00 | |||
LXR beta/NER/NR1H2 (H-8): m-IgG Fc BP-HRP Kit | sc-539868 | 200 µg Ab; 10 µg BP | $354.00 | |||
LXR beta/NER/NR1H2 (H-8): m-IgG1 BP-HRP Kit | sc-541754 | 200 µg Ab; 20 µg BP | $354.00 | |||
LXR beta/NER/NR1H2 (H-8) peptide neutralisant | sc-133221 P | 100 µg/0.5 ml | $68.00 | |||
Anticorps LXR beta/NER/NR1H2 (H-8) X | sc-133221 X | 200 µg/0.1 ml | $316.00 |