Lutropin β Antibody (A-9): sc-393284
- Lutropin β Antibody (A-9) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
- raised against amino acids 61-103 mapping within an internal region of Lutropin β of mouse origin
- recommended for detection of Lutropin β of mouse and rat origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Lutropin β Antibody (A-9) for WB applications. These reagents are now offered in bundles with Lutropin β Antibody (A-9) (see ordering information below).
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Lutropin β Antibody (A-9) is a mouse monoclonal IgG2b antibody that detects Lutropin β in mouse and rat samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Lutropin β, also known as luteinizing hormone (LH), is crucial for reproductive health as LH regulates key processes such as spermatogenesis in males and ovulation in females by stimulating the testes and ovaries to produce steroid hormones. The structure of Lutropin β is particularly important, as Lutropin β is a heterodimer composed of a common alpha chain and a unique beta chain, which is essential for biological activity and receptor binding. The presence of different isoforms of LH, resulting from proteolytic processing and metabolism, highlights the complexity of regulation and function in the endocrine system. Additionally, Lutropin β plays a role in modulating the processing of amyloid-beta precursor protein, which is significant in the context of neurodegenerative diseases. The spatial release of LH and follicle-stimulating hormone (FSH) from the pituitary gland through distinct circulatory routes further emphasizes the intricate mechanisms governing hormone secretion and action. Anti-Lutropin β antibody (A-9) is an invaluable tool for researchers studying reproductive biology and related disorders.
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Lutropin β Antibody (A-9) References:
- The role of luteinizing hormone in folliculogenesis and ovulation induction. | Filicori, M. 1999. Fertil Steril. 71: 405-14. PMID: 10065772
- Transgenic and knockout mouse models for the study of luteinizing hormone and luteinizing hormone receptor function. | Huhtaniemi, I., et al. 2002. Mol Cell Endocrinol. 187: 49-56. PMID: 11988311
- Luteinizing hormone and its dilemma in ovulation induction. | Kumar, P. and Sait, SF. 2011. J Hum Reprod Sci. 4: 2-7. PMID: 21772731
- Luteinizing hormone surge in normally ovulating women. | Alliende, ME. 2013. Fertil Steril. 99: e14-5. PMID: 23419930
- Luteinizing hormone contributes to fetal tolerance by regulating adaptive immune responses. | Schumacher, A., et al. 2014. Am J Reprod Immunol. 71: 434-40. PMID: 24592927
- Analysis of several bovine lutropin beta subunit cDNAs reveals heterogeneity in nucleotide sequence. | Maurer, RA. 1985. J Biol Chem. 260: 4684-7. PMID: 3838746
- Metabolic control of luteinizing hormone-responsive ovarian steroidogenesis. | Przygrodzka, E., et al. 2025. J Biol Chem. 301: 108042. PMID: 39615688
- Immunology of follicle-stimulating hormone and luteinizing hormone. | Lunenfeld, B. and Eshkol, A. 1969. Vitam Horm. 27: 131-97. PMID: 4911118
- Regulation of luteinizing hormone-releasing hormone and luteinizing hormone secretion by hypothalamic amino acids. | Donoso, AO., et al. 1994. Braz J Med Biol Res. 27: 921-32. PMID: 8087094
- Studies of disulfide bond location in ovine lutropin beta subunit. | Tsunasawa, S., et al. 1977. Biochim Biophys Acta. 492: 340-56. PMID: 884134
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Lutropin β Antibody (A-9) | sc-393284 | 200 µg/ml | $322.00 | |||
Lutropin β Antibody (A-9): m-IgG Fc BP-HRP Bundle | sc-538179 | 200 µg Ab; 10 µg BP | $361.00 | |||
Lutropin β Antibody (A-9): m-IgGκ BP-HRP Bundle | sc-535741 | 200 µg Ab; 40 µg BP | $361.00 |