Date published: 2025-9-9

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Anticorps LSP1 (16): sc-135976

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Fiches techniques
  • L'anticorps LSP1 16 est un monoclonal IgG1 de souris fourni en 50 µg/0.5 ml
  • dirigé contre les acides aminés 75-215 de LSP1 d'origine human
  • recommandé pour la détection de LSP1 d'origine human par WB, IP et IF; déconseillé pour IP
  • Nous testons actuellement encore nos anticorps secondaires pour trouver la meilleure protéine de liaison pour cet anticorps primaire LSP1 (16). Veuillez nous contacter si vous avez des questions concernant les réactifs de détection secondaire appropriés.

    ACCÈS RAPIDE AUX LIENS

    VOIR ÉGALEMENT...

    pp52 (human) or LSP1 (murine) is a hematopoietic-expressed gene that encodes an F-actin-binding, leukocyte-specific (including B and T lymphocytes, granulocytes and macrophages), phosphoprotein. However, mRNA splice variants that do not encode the lympho-specific protein are expressed from this gene in nonlymphoid cell lines as well (myocytes, stromal cells and fibroblasts), suggesting pp52 has a divergent role in signal transduction. The pp52 (LSP1) locus maps to human chromosome 11p15.5, which is implicated in tumor-related chromosomal translocations found in chronic lymphocytic leukemia. The pp52 promoter contains key elements that control transcriptional activity including an initiator specifying the unique 5' terminus of pp52 mRNA, tandem pairs of Ets and SP1 motifs, and a single C/EBP motif. LSP1 binds the cytoskeleton and has been implicated in affecting cytoskeletal remodeling in a variety of leukocyte functions, including cell motility and chemotaxis.

    Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

    Informations pour la commande

    Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

    Anticorps LSP1 (16)

    sc-135976
    50 µg/0.5 ml
    $316.00

    What is the recommended fixation method for immunofluorescence staining with LSP1 (16): sc-135976 monoclonal antibody?

    Posée par: cjMara
    Thank you for your inquiry. We recommend fixing cells for 5 minutes in -10ºC methanol and allowing to air dry. The full protocol can be viewed here: https://www.scbt.com/scbt/resources/protocols/immunofluorescence-cell-staining
    Répondue par: Technical Support
    Date de publication: 2017-03-24
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    Rated 4 de 5 de par Produced robust immunofluorescence nuclearProduced robust immunofluorescence nuclear staining in Jurkat cells. -SCBT QC
    Date de publication: 2015-02-22
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    Anticorps LSP1 (16) est évalué 4.0 de 5 de 2.
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