ACCÈS RAPIDE AUX LIENS
Lysyl hydroxylases (LLHs) 1-3 are hydroxylysines that function as attachment sites for carbohydrates. In collagen, the LLHs form hydroxylysine residues in -Xaa-Lys-Gly- sequences and are crucial for collagen crosslink stability. They form homodimers that localize to the endoplasmic reticulum. LLH1 is strongly expressed in liver, heart, lung, skeletal muscle and kidney tissue. LLH2 is highly expressed in heart, lung, kidney, eye, ovary and placenta, whereas LLH3 is expressed mainly in heart, lung, liver and testis. LLH3 is a 738 amino acid, multifunctional enzyme with lysyl hydroxylase, hydroxylysyl galactosyltransferase and galactosylhydroxylysyl glucosyltransferase activities. LLH3 is necessary for the formation of the basement membrane and its gene expression is tightly regulated in adult tissues. Defects in the LLH3 gene commonly lead to heritable disorders of connective tissue and loss of LLH3 results in embryonic lethality.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps LLH3 (G-3) | sc-137193 | 200 µg/ml | $316.00 | |||
LLH3 (G-3): m-IgG Fc BP-HRP Kit | sc-537419 | 200 µg Ab; 10 µg BP | $354.00 | |||
LLH3 (G-3): m-IgGκ BP-HRP Kit | sc-534676 | 200 µg Ab; 40 µg BP | $354.00 | |||
LLH3 (G-3): m-IgG1 BP-HRP Kit | sc-545179 | 200 µg Ab; 20 µg BP | $354.00 | |||
LLH3 (G-3) peptide neutralisant | sc-137193 P | 100 µg/0.5 ml | $68.00 |