Anticorps Listeria monocytogenes (LX99): sc-66105

The genus Listeria includes the species Listeria monocytogenes, a gram-positive bacterium that is motile by means of flagella, though it can also move inside of eukaryotic cells by polymerizing actin comet tails with a protein called ActA. L. monocytogenes is the only species of the genus Listeria that has been clearly documented as a pathogen for humans. It is food-borne, intracellular, and interacts with infected host cells both prior to entry and during the intracellular phase of infection. Uptake by the host cell is stimulated by the binding of listerial internalins (Inl) to host cell adhesion factors such as E-cadherin or Met, which then exploits the junction forming-apparatus of the host into internalizing the bacterium. Infection by L. monocytogenes causes the disease listeriosis, which can manifest into meningitis and septicemia. Listeriosis occurs mainly in newborn infants, elderly patients, and patients who are immunocompromised.