ACCÈS RAPIDE AUX LIENS
VOIR ÉGALEMENT...
Liprins interact with members of the leukocyte common antigen-related (LAR) family of transmembrane protein tyrosine phosphatases, which are implicated in axon guidance and mammary gland development. Liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR phosphatases. Based on sequence similarites and binding characteristics, liprins are subdivided into α-type and β-type liprins. Both α- and β-liprins homodimerize via their N-terminal, coiled coil regions. Liprin β2 is expressed strongly in liver, kidney, intestine, heart, lung and testis, however it can be detected at low levels in brain and thymus. Four isoforms exist for Liprin β2 due to splicing variants. Isoform 1 respresents the full length protein. Isoform 2 lacks amino acids 459-469. Isoform 3 contains an alternative sequence for amino acids 127-200 and is truncated at amino acid 200. Isoform 4 lacks amino acids 459-469 and contains an alternative sequence for amino acids 877-882.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps Liprin β2 (H-6) | sc-376444 | 200 µg/ml | $316.00 | |||
Liprin β2 (H-6): m-IgG Fc BP-HRP Kit | sc-540571 | 200 µg Ab; 10 µg BP | $354.00 | |||
Liprin β2 (H-6): m-IgG1 BP-HRP Kit | sc-542214 | 200 µg Ab; 20 µg BP | $354.00 |