ACCÈS RAPIDE AUX LIENS
VOIR ÉGALEMENT...
LIN-41, also called tripartite motif-containing 71 (TRIM71), which was first identified in Caenorhabditis elegans, is responsible for the timing of cell fate determination. By encoding microRNAs (miRNAs), the heterochronic genes let-7 and lin-4 downregulate the gene encoding LIN-41. The miRNAs bind to six complementary sites on the 3' untranslated region (UTR) of the LIN-41 gene. This downregulation positively regulates the timing of the expression of LIN-29, an adult specification transcription factor. Null mutations in the gene encoding LIN-41 lead to the premature development of adult tissues during larval stages. Although LIN-41 is expressed in many different embryonic cell types, it is most highly expressed in the developing limb buds, tail buds and brachial arches.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps LIN-41 (B-12) | sc-393338 | 200 µg/ml | $316.00 | |||
LIN-41 (B-12): m-IgG2a BP-HRP Kit | sc-546078 | 200 µg Ab; 10 µg BP | $354.00 |