Anticorps LEPREL1 (B-9): sc-377353
- L'Anticorps LEPREL1 (B-9) est un monoclonal de souris IgG2a (chaîne légère kappa) fourni en 200 µg/ml
- dirigé contre les acides aminés 317-442 dans une région interne de LEPREL1 d'origine human
- recommandé pour la détection de LEPREL1 d'origine human par WB, IP, IF et ELISA
- Le m-IgG Fc BP-HRP est le réactif de détection secondaire préféré pour l'anticorps LEPREL1 (B-9) pour les applications WB. Ce réactif est désormais proposé en bundle avec l'anticorps LEPREL1 (B-9)(voir les informations de commande ci-dessous).
ACCÈS RAPIDE AUX LIENS
LEPREL1 (leprecan-like 1), also known as P3H2 (Prolyl 3-hydroxylase 2 precursor) or MLAT4 (myxoid liposarcoma-associated protein 4), is a 708 amino acid protein that belongs to a family of collagen prolyl hydroxylases. LEPREL1 has a highly conserved C-terminal domain that contains critical catalytic residues found in lysyl and prolyl 4-hydroxylases, including 2 iron-binding histidines and an aspartic acid. LEPREL1 is expressed in heart, placenta, lung, liver, skeletal muscle and kidney. Expression is localized to the epithelia of bile ducts and to the sarcoplasm of heart muscle and skeletal muscle. LEPREL1 is required for proper collagen biosynthesis, folding, and assembly. LEPREL1 forms a complex with cartilage-associated protein (CRTAP) and cyclophilin B (CyPB) in the endoplasmic reticulum. This complex is responsible for 3-hydroxylation of proline residues of collagen type I, II and V, and is important for normal bone development.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps LEPREL1 (B-9) | sc-377353 | 200 µg/ml | $316.00 | |||
LEPREL1 (B-9): m-IgG Fc BP-HRP Kit | sc-540711 | 200 µg Ab; 10 µg BP | $354.00 |