Date published: 2025-9-8

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Anticorps LCMT1 (C-8): sc-365064

5.0(1)
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Fiches techniques
  • L'Anticorps LCMT1 (C-8) est un monoclonal de souris IgG2a κ, cité dans 1 publications, fourni en 200 µg/ml
  • dirigé contre les acides aminés 179-334 situés au niveau C-terminus de LCMT1 d'origine human
  • recommandé pour la détection de LCMT1 d'origine human par WB, IP, IF et ELISA
  • Le m-IgGκ BP-HRP est le réactif de détection secondaire préféré pour l'anticorps LCMT1 (C-8) pour les applications WB. Ce réactif est désormais proposé en association avec l'anticorps LCMT1 (C-8)(voir les informations relatives à la commande ci-dessous). Pour d'autres conjugués m-IgGκ BP, voir notre liste complète de protéines de liaison à l'IgG de souris.

ACCÈS RAPIDE AUX LIENS

VOIR ÉGALEMENT...

Protein phosphatase 2A (PP2A) is a Serine/Threonine (Ser/Thr) phosphatase that is thought to be involved in cell growth and proliferation events and may be associated with tumor progression. The activity of PP2A is regulated by a variety of mechanisms, one of which is the reversible methylation by select methyltransferases. LCMT1 (leucine carboxyl methyltransferase 1), also known as LCMT, PPMT1 or CGI-68, is a 334 amino acid member of the methyltransferase superfamily that is involved in the regulation of PP2A. Specifically, LCMT1 catalyzes the methylation of the carboxy group on the C-terminal leucine of the PP2A catalytic subunit (designated PP2Aα). Via its ability to regulate PP2A function, LCMT1 may be critical for normal mitotic progression and overall cell survival. Two isoforms of LCMT1 are expressed due to alternative splicing events.

Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

Informations pour la commande

Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

Anticorps LCMT1 (C-8)

sc-365064
200 µg/ml
$316.00

LCMT1 (C-8): m-IgGκ BP-HRP Kit

sc-535143
200 µg Ab; 40 µg BP
$354.00

Since the immunogens of these antibodies are both 179aa-334aa of hLCMT1, what is the difference between F-4, D-10, and C-8? Which one is better for WB and IF? Thanks.

Posée par: Henearkrxern
Thank you for your question. They are different clones, and all recommended for detection of LCMT1 of human origin of cells and frozen tissue sections by WB and IF.
Répondue par: Technical Support 12
Date de publication: 2021-08-31

For Western Blot, is it recommended to use denatured or non-denatured conditions with LCMT1 (C-8): sc-365064 monoclonal antibody?

Posée par: Randy McDonald
Thank you for your question. We recommend this antibody for use in denatured Western Blot conditions. It has not been validated for use in non-denatured conditions. Please contact our Technical Service Department for further details or inquiries.
Répondue par: Technical Support
Date de publication: 2017-02-27
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Rated 5 de 5 de par Produced nice Western blot data of LCMT1Produced nice Western blot data of LCMT1 expression in 293 whole cell lysate. -SCBT QC
Date de publication: 2013-05-13
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Anticorps LCMT1 (C-8) est évalué 5.0 de 5 de 1.
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