ACCÈS RAPIDE AUX LIENS
Junctophilins are components of the junctional complexes between plasma membranes and endoplasmic or sarcoplasmic reticulums present in all excitable cells. Junctophilins contain a cytoplasmic domain which binds to the plasma membrane, as well as an ER/SR membrane spanning hydrophobic C-terminal segment. The three subtypes in this family are Junctophilin-1, -2 and -3. Junctophilin-1 is predominantly expressed in skeletal muscle, but is also expressed at low levels in heart. Junctophilin-2 is expressed in heart and skeletal muscle. Mutant mice lacking the Jph2 gene exhibit embryonic lethality and possess cardiac myocytes that express abnormal calcium transients. Junctophilin-3 is expressed in brain. The JPH3 alternatively spliced exon 2A has been suggested as a site for CTG repeat expansion leading to a Huntington disease-like autosomal dominant disorder.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps Junctophilin-2 (B-6) | sc-398125 | 200 µg/ml | $316.00 | |||
Junctophilin-2 (B-6): m-IgG Fc BP-HRP Kit | sc-538373 | 200 µg Ab; 10 µg BP | $354.00 | |||
Junctophilin-2 (B-6): m-IgGκ BP-HRP Kit | sc-535975 | 200 µg Ab; 40 µg BP | $354.00 | |||
Junctophilin-2 (B-6): m-IgG1 BP-HRP Kit | sc-545667 | 200 µg Ab; 20 µg BP | $354.00 | |||
Junctophilin-2 (B-6) peptide neutralisant | sc-398125 P | 100 µg/0.5 ml | $68.00 |