Date published: 2025-9-10

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Anticorps JRAB (G-10): sc-376791

5.0(2)
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Fiches techniques
  • L'Anticorps JRAB (G-10) est un monoclonal de souris IgG2a (chaîne légère kappa) fourni en 200 µg/ml
  • dirigé contre les acides aminés 561-664 dans une région interne de JRAB d'origine human
  • recommandé pour la détection de JRAB d'origine human par WB, IP, IF et ELISA
  • 2a BP-HRP">m-IgG2a BP-HRP est le réactif de détection secondaire préféré pour l'anticorps JRAB (G-10) pour les applications WB. Ce réactif est désormais proposé en association avec l'anticorps JRAB (G-10)(voir les informations relatives à la commande ci-dessous).

    ACCÈS RAPIDE AUX LIENS

    VOIR ÉGALEMENT...

    JRAB (junctional Rab13-binding protein, MICAL-like protein 2) is a 904 amino acid protein with one CH (calponin-homology) domain and one LIM zinc-binding domain. JRAB has been shown to interact with Rab13 and Rab8 to facilitate cellular transport of claudin-1, occludin, and E-cadherin. This interaction is vital for the coordination of the assembly of tight junctions (TJs) and adherens junctions (AJs). Dynamic turnover (endocytic recycling) of cell-to-cell AJs and TJs is essential for epithelial morphogenesis during normal development and differentiation. The endocytic recycling of occludin and cluadin proteins is part of an ongoing process of restructuring and maintaining cell junctions, especially at TJs. JRAb and Rab13 have also been implicated in the carcinoma metastasis event of epithelial cell scattering. This event shows Rab13 and JRAB colocalizing with F-Actin in lamellipodial structures prior to cell scattering.

    Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

    Informations pour la commande

    Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

    Anticorps JRAB (G-10)

    sc-376791
    200 µg/ml
    $316.00

    JRAB (G-10): m-IgG2a BP-HRP Kit

    sc-546063
    200 µg Ab; 10 µg BP
    $354.00

    How much sample do you recommend loading on the gel for Western blot detection using JRAB (G-10): sc-376791?

    Posée par: Professor Griffin
    We recommend loading 40–60 µg whole cell lysate, 10–20 µg nuclear extract, 5-10 µg transfected lysate, or 10–20 ng purified protein per lane. A link to our complete Western blotting protocol is provided here for your reference: https://www.scbt.com/scbt/resources/protocols/western-immuno-blotting
    Répondue par: Technical Support
    Date de publication: 2017-03-01
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    Rated 5 de 5 de par Nice Western Blot data of JRAB expression in WINice Western Blot data of JRAB expression in WI-38 and MCF7 whole cell lysates. -SCBT QC
    Date de publication: 2015-01-10
    Rated 5 de 5 de par Nice Western Blot data of JRAB expression in nonNice Western Blot data of JRAB expression in non-transfected and human JRAB transfected 293T whole cell lysates. -SCBT QC
    Date de publication: 2014-01-23
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    Anticorps JRAB (G-10) est évalué 5.0 de 5 de 2.
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