Anticorps JAM-A (J3F.1): sc-53622
- L'Anticorps JAM-A (J3F.1) est un monoclonal de souris IgG1 κ, cité dans 5 publications, fourni en 200 µg/ml
- élevé contre la protéine de fusion JAM recombinante d'origine human.
- recommandé pour la détection de JAM-A d'origine human par WB, IP, IF, IHC(P) et FCM
- disponible conjugué soit à la phycoérythrine soit à la FITC pour IF, IHC(P) et FCM
- Voir JAM-A (J10.4): sc-53623 pour d'autres anticorps conjugués JAM-A, dont AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 et 790.
- m-IgG Fc BP-HRP et m-IgG1 BP-HRP sont les réactifs secondaires recommandés pour la détection de l'anticorps JAM-A (J3F.1) pour des applications de WB and IHC(P). Ces réactifs sont maintenant proposés en kit avec l'anticorps JAM-A (J3F.1) (voir Informations pour la commande ci-dessous).
Junctional adhesion molecule (JAM) is a member of the immunoglobulin superfamily expressed in tight junctions of epithelial cells and endothelial cells. It is implicated in transendothelial migration of leukocytes. JAM is constitutively expressed on circulating monocytes, neutrophils, lymphocyte subsets and platelets. The JAM family consists of JAM-A, JAM-B and JAM-C, alternatively designated JAM-1, JAM-2 and JAM-3, respectively. JAM-A localizes with F-Actin at the cell-cell contacts and at the membrane ruffles. It is involved in cell to cell adhesion through homophilic interactions and plays a role in the organization of tight junctions and modulation of leukocyte extravasation. JAM-B interacts with discrete subsets of PBLs, suggesting that it may play a role in lymphocyte trafficking. JAM-B and JAM-C proteins are binding partners; JAM-C may be a functional JAM-B receptor. Specifically, JAM-B adheres to T cells through heterotypic interactions with JAM-C. The JAM-B/JAM-C interaction may play a role in T, NK and dendritic cellular inflammation.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps JAM-A (J3F.1) | sc-53622 | 200 µg/ml | $316.00 | |||
JAM-A (J3F.1): m-IgG Fc BP-HRP Kit | sc-538999 | 200 µg Ab; 10 µg BP | $354.00 | |||
JAM-A (J3F.1): m-IgG1 BP-HRP Kit | sc-541200 | 200 µg Ab; 20 µg BP | $354.00 | |||
Anticorps JAM-A (J3F.1) FITC | sc-53622 FITC | 200 µg/ml | $330.00 | |||
Anticorps JAM-A (J3F.1) PE | sc-53622 PE | 200 µg/ml | $343.00 |