Date published: 2025-9-8

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Anticorps IQGAP1 (F-7): sc-376383

5.0(1)
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Fiches techniques
  • L'Anticorps IQGAP1 (F-7) est un monoclonal de souris IgG2a κ, cité dans 1 publications, fourni en 200 µg/ml
  • dirigé contre les acides aminés 314-422 situés près de la région N-terminus de IQGAP1 d'origine human
  • recommandé pour la détection de IQGAP1 d'origine mouse, rat et human par WB, IP, IF, IHC(P) et ELISA
  • Voir IQGAP1 (C-9): sc-376021 pour d'autres anticorps conjugués IQGAP1, dont AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 et 790.
  • m-IgG Fc BP-HRP et 2a BP-HRP">m-IgG2a BP-HRP sont les réactifs de détection secondaire préférés pour IQGAP1 Antibody (F-7) pour les applications WB et IHC(P). Ces réactifs sont désormais proposés en lots avec IQGAP1 Antibody (F-7)(voir les informations de commande ci-dessous).

ACCÈS RAPIDE AUX LIENS

VOIR ÉGALEMENT...

IQGAP1, for IQ motif containing GTPase activating protein, is a Ras GAP-related, Actin-binding protein that interacts with the small GTPases Cdc42 and Rac1. The C-terminus of IQGAP1 is essential for interacting with Cdc42 and, in addition, IQGAP1 contains a WW domain and a predicted N-terminal coiled-coil region, which may be involved in IQGAP dimerization. Expression of IQGAP1 is highest in placenta, lung and kidney, where it co-localizes with Cdc42 to the cytoskeleton and assists with Cdc42 in mediating the regulation of cell proliferation, polarity and cell morphology. IQGAP1 regulates cadherin-mediated cell adhesion via binding to E-cadherin, b-catenin and a-catenin. This association induces the accumulation of these proteins at the site of cell-cell contact. IQGAP1 is negatively regulated by calmodulin, which binds to IQGAP1 in a calcium-dependent manner and disrupts IQGAP1 from associating with Cdc42.

Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

Informations pour la commande

Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

Anticorps IQGAP1 (F-7)

sc-376383
200 µg/ml
$316.00

IQGAP1 (F-7): m-IgG Fc BP-HRP Kit

sc-540557
200 µg Ab; 10 µg BP
$354.00

IQGAP1 (F-7): m-IgG2a BP-HRP Kit

sc-546924
200 µg Ab; 10 µg BP
$354.00

Can IQGAP1 (F-7): sc-376383 monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

Posée par: Germaine
Thank you for your question. Yes, IQGAP1 (F-7): sc-376383 has been validated for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Répondue par: Technical Support
Date de publication: 2017-02-27
  • y_2025, m_8, d_28, h_5CST
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Rated 5 de 5 de par Produced positive Western blot data of IQGAP1Produced positive Western blot data of IQGAP1 expression in KNRK whole cell lysate. -SCBT QC
Date de publication: 2014-10-21
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Anticorps IQGAP1 (F-7) est évalué 5.0 de 5 de 1.
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