Date published: 2025-9-8

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Anticorps IMP-1/IGF2BP1 (G-8): sc-390149

5.0(1)
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Fiches techniques
  • L'Anticorps IMP-1/IGF2BP1 (G-8) est un monoclonal de souris IgG1 κ, cité dans 2 publications, fourni en 200 µg/ml
  • soulevée contre une cartographie peptidique dans une région interne de IGF2BP1 d'origine human.
  • recommandé pour la détection de IGF2BP1 d'origine mouse, rat et human par WB, IP, IF et ELISA; également réactif avec d'autres espèces, dont et equine, canine, bovine and porcine
  • m-IgG Fc BP-HRP et 1 BP-HRP">m-IgG1 BP-HRP sont les réactifs de détection secondaire préférés pour IMP-1/IGF2BP1 Antibody (G-8) for WB applications. Ces réactifs sont désormais proposés en lots avec IMP-1/IGF2BP1 Antibody (G-8)(voir les informations de commande ci-dessous).

ACCÈS RAPIDE AUX LIENS

VOIR ÉGALEMENT...

Insulin like growth factor 2 mRNA binding proteins (IGF2BPs) bind RNA and influence RNA synthesis and metabolism. IGF2BP1, also known as coding region determinant-binding protein/insulin-like growth factor II mRNA-binding protein (CRD-BP), IMP1 or VICKZ1; IGF2BP2 (IMP2, VICKZ2, p62); and IGF2BP3 (IMP3, KOC1, VICKZ3) contain a unique combination of RNA recognition motifs and four hnRNP K homology domains. IGF2BP1 is abundant in embryonal tissues and is expressed in 81% of colon cancers, 73% of sarcomas and 58.5% of breast cancers. It recognizes c-Myc, IGF-II and t mRNAs, and H19 RNA, and plays a major role in proliferation of K-562 cells by an IGF-II-dependent mechanism. IGF2BP2 binds the 5' UTR of IGF-II mRNA and influences tumor cell growth, in which IGF2BP2 is associated with apoptosis induced by tretinoin. IGF2BP3 knockdown by RNA interference decreases levels of IGF-II protein without affecting IGF-II, c-Myc, or β Actin mRNA and H19 RNA levels. IGF2BP3 is a marker for carcinomas and high-grade dysplastic lesions of pancreatic ductal epithelium.

Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

Informations pour la commande

Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

Anticorps IMP-1/IGF2BP1 (G-8)

sc-390149
200 µg/ml
$316.00

IMP-1/IGF2BP1 (G-8): m-IgG Fc BP-HRP Kit

sc-540763
200 µg Ab; 10 µg BP
$354.00

IMP-1/IGF2BP1 (G-8): m-IgG1 BP-HRP Kit

sc-542355
200 µg Ab; 20 µg BP
$354.00

IMP-1/IGF2BP1 (G-8) peptide neutralisant

sc-390149 P
100 µg/0.5 ml
$68.00

What application is the blocking peptide sc-390149 P appropriate for?

Posée par: Cweed
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Répondue par: Technical Support
Date de publication: 2017-02-25
  • y_2025, m_8, d_27, h_5CST
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Rated 5 de 5 de par Produced positive Western blot data of IMPProduced positive Western blot data of IMP-1 expression in P19 whole cell lysate. -SCBT QC
Date de publication: 2014-01-05
  • y_2025, m_8, d_27, h_5
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Anticorps IMP-1/IGF2BP1 (G-8) est évalué 5.0 de 5 de 1.
  • y_2025, m_8, d_27, h_5
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