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The Hep C (hepatitis C) is a small, enveloped, single-stranded, positive sense RNA virus belonging to the family Flaviviridae. Transmission of the virus occurs when blood from an infected individual enters the body of an uninfected individual. Hep C primarily replicates within hepatocytes in the liver, and circulating Hep C particles bind to receptors on the surface and enter these cells. Hep C replicates quickly, producing approximately one trillion particles each day in infected individuals. Hep C RNA polymerase has no proofreading function, so the virus has an exceptionally high mutation rate which may help it elude the immune system of the host. Hep C infection results in chronic infections, liver cirrhosis and hepatocellular carcinoma in most people. The transmembrane (TM) domains of Hep C envelope glycoproteins E1 and E2 play multiple functions during the biogenesis of the E1E2 heterodimer. E1 and E2 also play an important role in cell entry.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps Hep C E2 (BDI167) | sc-57769 | 100 µg/ml | $316.00 |