HCNP Antibody (F-1): sc-271038
- HCNP Antibody (F-1) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against amino acids 556-855 mapping at the C-terminus of HCNP of human origin
- recommended for detection of HCNP of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for HCNP Antibody (F-1) for WB applications. These reagents are now offered in bundles with HCNP Antibody (F-1) (see ordering information below).
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HCNP Antibody (F-1) is a mouse monoclonal IgG1 antibody that detects HCNP in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). HCNP, also known as XAB2, plays a crucial role in cellular response to DNA damage, particularly in transcription-coupled repair and pre-mRNA splicing. HCNP is primarily located in the nucleus, where HCNP interacts with key components of nucleotide excision repair machinery, including Cockayne syndrome group A and B proteins, RNA Polymerase II, and XPA. Nuclear localization of HCNP is vital for function, allowing timely repair of damaged DNA and proper processing of pre-mRNA, ensuring accurate gene expression regulation. Furthermore, HCNP is an essential part of the spliceosome complex, responsible for removing introns from pre-mRNA, facilitating production of mature mRNA necessary for protein synthesis. Given involvement in critical cellular processes, HCNP influences cell differentiation and proliferation in cancer biology, making anti-HCNP antibody (F-1) a valuable tool for researchers studying these pathways.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
HCNP Antibody (F-1) | sc-271038 | 200 µg/ml | $322.00 | |||
HCNP Antibody (F-1): m-IgG Fc BP-HRP Bundle | sc-540195 | 200 µg Ab; 10 µg BP | $361.00 | |||
HCNP Antibody (F-1): m-IgG1 BP-HRP Bundle | sc-541963 | 200 µg Ab; 20 µg BP | $361.00 |