Anticorps granzyme M (C-10): sc-393375
- L'Anticorps granzyme M (C-10) est un monoclonal de souris IgG1 (chaîne légère kappa) fourni en 200 µg/ml
- spécifique d'un épitope situé entre les acides aminés 82-129 au niveau d'une région interne de granzyme M d'origine human
- recommandé pour la détection de granzyme M d'origine mouse, rat et human par WB, IP, IF et ELISA
- m-IgG Fc BP-HRP, 1 BP-HRP">m-IgG1 BP-HRP et m-IgGκ BP-HRP sont les réactifs de détection secondaire préférés pour l'anticorps granzyme M (C-10) pour les applications WB. Ces réactifs sont désormais proposés en lots avec l'anticorps granzyme M (C-10)(voir les informations de commande ci-dessous).
ACCÈS RAPIDE AUX LIENS
VOIR ÉGALEMENT...
The granzyme family of proteins belong to the larger peptidase S1 family. Granzyme A and granzyme B are serine proteases that facilitate apoptotic signaling in cytotoxic T lymphocytes (CTL) and natural killer (NK) cells. Within the granules of activated CTLs, granzyme A and granzyme B are processed and converted to their active forms by the lysosomal cysteine protease cathepsin C. Once cleaved, these active proteases target distinct substrates for proteolysis, thereby mediating apoptosis through two different pathways. Granzyme H localizes to cytoplasmic granules of cytolytic T lymphocytes and is important for target cell lysis in cell-mediated immune responses. Granzyme K is a serine protease localizing to the granules of NK cells and cytotoxic T lymphocytes. Granzyme M (also designated NK cell granular protease, HU-Met-1 or met-1 serine protease) contains one peptidase S1 domain. Granzyme M is a Trypsin-fold serine protease that localizes to granules of large granular lymphocytes (NK cells) and cleaves peptide substrates after leucine, norleucine or methionine. This enzyme may play a role in target cell death induction by cytotoxic lymphocytes.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps granzyme M (C-10) | sc-393375 | 200 µg/ml | $316.00 | |||
granzyme M (C-10): m-IgG Fc BP-HRP Kit | sc-538199 | 200 µg Ab; 10 µg BP | $354.00 | |||
granzyme M (C-10): m-IgGκ BP-HRP Kit | sc-535767 | 200 µg Ab; 40 µg BP | $354.00 | |||
granzyme M (C-10): m-IgG1 BP-HRP Kit | sc-545573 | 200 µg Ab; 20 µg BP | $354.00 | |||
granzyme M (C-10) peptide neutralisant | sc-393375 P | 100 µg/0.5 ml | $68.00 |