Date published: 2025-9-9

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Anticorps Grancalcin (G-1): sc-365835

5.0(2)
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Fiches techniques
  • L'Anticorps Grancalcin (G-1) est un monoclonal de souris IgG2b (chaîne légère kappa) fourni en 200 µg/ml
  • spécifique d'un épitope situé entre les acides aminés 21-55 près de N-terminus de grancalcin d'origine human
  • recommandé pour la détection de Grancalcin d'origine human par WB, IP, IF et ELISA
  • 2b BP-HRP">m-IgG2b BP-HRP et m-IgGκ BP-HRP sont les réactifs de détection secondaire préférés pour l'anticorps Grancalcin (G-1) pour les applications WB. Ces réactifs sont désormais proposés en lots avec l'anticorps Grancalcin (G-1)(voir les informations relatives à la commande ci-dessous).

    ACCÈS RAPIDE AUX LIENS

    VOIR ÉGALEMENT...

    Grancalcin is a calcium-binding protein that is especially abundant in human neutrophils. Grancalcin belongs to the penta EF-hand (PEF) subfamily of EF-hand proteins, which also comprises calpain, sorcin, peflin and ALG-2. Grancalcin forms a homodimer through the association of the unpaired EF5 hands. Grancalcin undergoes important conformational changes upon binding of calcium, which subsequently exposes hydrophobic amino acid residues to direct the protein to hydrophobic surfaces. Grancalcin interacts with L-plastin, a protein known to have actin bundling activity, which suggests that grancalcin may play a role in the regulation of neutrophil adhesion. Grancalcin is specifically associated with cells originating in the bone marrow, and it is particularly abundant in neutrophils and monocytes, with relatively small amounts detected in lymphocytes.

    Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

    Informations pour la commande

    Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

    Anticorps Grancalcin (G-1)

    sc-365835
    200 µg/ml
    $316.00

    Grancalcin (G-1): m-IgGκ BP-HRP Kit

    sc-535267
    200 µg Ab; 40 µg BP
    $354.00

    Grancalcin (G-1): m-IgG2b BP-HRP Kit

    sc-549379
    200 µg Ab; 10 µg BP
    $354.00

    Grancalcin (G-1) peptide neutralisant

    sc-365835 P
    100 µg/0.5 ml
    $68.00

    What application is the blocking peptide sc-365835 P appropriate for?

    Posée par: AbPolly
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Répondue par: Technical Support
    Date de publication: 2017-03-01
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    Rated 5 de 5 de par Nice Western Blot data of Grancalcin expressionNice Western Blot data of Grancalcin expression in HL-60 and AML-193 whole cell lysates. -SCBT QC
    Date de publication: 2015-02-09
    Rated 5 de 5 de par Produced positive Western Blot data of GrancalcinProduced positive Western Blot data of Grancalcin expression in THP-1 and MCF7 whole cell lysates. -SCBT QC
    Date de publication: 2013-08-27
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    Anticorps Grancalcin (G-1) est évalué 5.0 de 5 de 2.
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