Date published: 2025-9-7

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Anticorps GMEB-1 (LL-18): sc-100753

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Fiches techniques
  • L'Anticorps GMEB-1 (LL-18) est un monoclonal de souris IgG2a (chaîne légère kappa) fourni en 100 µg/ml
  • dirigé contre la GMEB-1 recombinante d'origine human
  • recommandé pour la détection de GMEB-1 d'origine human par WB, IP, IF, IHC(P) et ELISA
  • Nous testons actuellement encore nos anticorps secondaires pour trouver la meilleure protéine de liaison pour cet anticorps primaire GMEB-1 (LL-18). Veuillez nous contacter si vous avez des questions concernant les réactifs de détection secondaire appropriés.

    ACCÈS RAPIDE AUX LIENS

    VOIR ÉGALEMENT...

    GMEB-1 (Glucocorticoid modulatory element-binding protein 1), also known as PIF p96 (Parvovirus initiation factor p96), is a 573 amino acid protein that contains one SAND domain and is a member of the KDWK family of combinatorial transcription modulators. Localized to both the cytoplasm and the nucleus, GMEB-1 forms a heterodimer with GMEB-2 (Glucocorticoid modulatory element-binding protein 2) and, once associated with GMEB-2, plays a key role in parvovirus DNA replication. In addition, GMEB-1 functions alone as a trans-acting factor that, by binding to glucocorticoid modulatory elements (GMEs) in TAT (tyrosine aminotransferase) promoters, increases intracellular sensitivity to glucocorticoid concentrations. GMEB-1 also interacts with initiator procaspases and, via this interaction, can inhibit caspase-induced apoptosis. Due to alternative splicing events, GMEB-1 is expressed as two isoforms.

    Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

    Informations pour la commande

    Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

    Anticorps GMEB-1 (LL-18)

    sc-100753
    100 µg/ml
    $333.00

    Can sc-100753: GMEB-1 (LL-18) monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

    Posée par: Dr Ninau Qelp
    Thank you for your question. Yes, sc-100753: GMEB-1 (LL-18) is recommended for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
    Répondue par: Technical Support
    Date de publication: 2017-03-24
    • y_2025, m_8, d_28, h_5CST
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    Rated 4 de 5 de par Robust immunoperoxidase nuclear and cytoplasmicRobust immunoperoxidase nuclear and cytoplasmic staining in formalin-fixed, paraffin-embedded human colon tissue. -SCBT QC
    Date de publication: 2015-03-01
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    Anticorps GMEB-1 (LL-18) est évalué 4.0 de 5 de 2.
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