ACCÈS RAPIDE AUX LIENS
Human GAP1-InsP4 BP, also designated Ras p21 protein activator (GTPase-activating protein) 3 [Ins(1,3,4,5)P4-binding protein], is an 829-amino acid protein that binds phospholipids in both a calcium-dependent and -independent manner. GAP1, one of the Ras GTPase-activating protein families, comprises four distinct genes, including GAP1(m), GAP1-InsP4 BP, MRASAL (murine Ras GTPase-activating-like) and KIAA0538. This family contains an N-terminal tandem C2 domain, a GAP-related domain and a C-terminal pleckstrin homology (PH) domain. The PH domains of GAP1-InsP4 BP are essential for membrane targeting via binding of specific phospholipids. Following agonist-stimulated PtdIns(3,4,5)P(3) production, group I family PH domain containing proteins like GAP1-InsP4 BP specifically bind inositol phosphates, which are subsequently targeted to the plasma membrane.
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Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps GAP1-InsP4 BP (H-6) | sc-374555 | 200 µg/ml | $316.00 | |||
GAP1-InsP4 BP (H-6): m-IgG Fc BP-HRP Kit | sc-540473 | 200 µg Ab; 10 µg BP | $354.00 | |||
GAP1-InsP4 BP (H-6) peptide neutralisant | sc-374555 P | 100 µg/0.5 ml | $68.00 |