Anticorps GABP-β1/2 (11): sc-130315
- L'Anticorps GABP-β1/2 (11) est un monoclonal de souris mouse IgG2a κ κ, cité dans 1 publications, fourni en 200 µg/ml
- dirigé contre la GABP-β1/2 recombinante d'origine human
- recommandé pour la détection de GABP-β1 and GABP-β2 d'origine mouse, rat et human par WB, IP et ELISA
- m-IgG Fc BP-HRP et 2a BP-HRP">m-IgG2a BP-HRP sont les réactifs de détection secondaire préférés pour GABP-β1/2 Antibody (11) pour les applications WB. Ces réactifs sont désormais proposés en lots avec GABP-β1/2 Antibody (11)(voir les informations de commande ci-dessous).
The transcription factor GA-binding protein (GABP) is composed of two subunits, the Ets-related GABP-α and a GABP-α-associated subunit, GABPβ. GABPα binds to a specific DNA sequence and GABPβ exists as β1 and β2 splice variants that differ in their C-termini. In primary neuronal cultures, GABPβ is expressed in both the cytoplasm and the nucleus, whereas GABPα is expressed mainly in the nucleus. GABP is constitutively expressed as either a GABPαβ heterodimer or a GABPαβ heterotetramer, both of which can modify GABP-dependent transcription in vitro and in vivo. The GABPαβ tetrameric complex performs many different functions, such as stimulating transcription of the adenovirus E4 gene, differentially activating BRCA1 expression in human breast cell lines, potentiating Tat-mediated activation of long terminal repeat promoter transcription and viral replication in certain cell types, acting as a coordinator of mitochrondrial and nuclear transcription for cytochrome oxidase in neurons and assisting in the regulation of rpL32 gene transcription.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps GABP-β1/2 (11) | sc-130315 | 200 µg/ml | $316.00 | |||
GABP-β1/2 (11): m-IgG Fc BP-HRP Kit | sc-539811 | 200 µg Ab; 10 µg BP | $354.00 | |||
GABP-β1/2 (11): m-IgG2a BP-HRP Kit | sc-546787 | 200 µg Ab; 10 µg BP | $354.00 |