Date published: 2025-9-10

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Anticorps FOXM1 (E-10): sc-376621

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Fiches techniques
  • L'Anticorps FOXM1 (E-10) est un monoclonal de souris IgG1 κ, cité dans 4 publications, fourni en 200 µg/ml
  • spécifique d'un épitope situé entre les acides aminés 735-763 au niveau C-terminus de FOXM1 d'origine human
  • recommandé pour la détection de all isoforms of FOXM1 d'origine mouse, rat et human par WB, IP, IF et ELISA
  • Réactifs TransCruz pour une application en ChIP (sc-376621 X, 200 µg/0.1 ml)
  • Voir FOXM1 (G-5): sc-376471 pour d'autres anticorps conjugués FOXM1, dont AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 et 790.
  • m-IgG Fc BP-HRP et 1 BP-HRP">m-IgG1 BP-HRP sont les réactifs de détection secondaire préférés pour FOXM1 Antibody (E-10) for WB applications. Ces réactifs sont désormais proposés en lots avec FOXM1 Antibody (E-10)(voir les informations de commande ci-dessous).

ACCÈS RAPIDE AUX LIENS

VOIR ÉGALEMENT...

The Fox family of transcription factors is a large group of proteins that share a common DNA binding domain termed a winged-helix or forkhead domain. FOXM1, also known as FKHL16, MPP2 or Trident, is primarily expressed in proliferating cells. The gene encoding human FOXM1 maps to chromosome 12p13. The transcription element that restricts FOXM1 expression to proliferating cells is located 300 bp upstream of the start codon. FOXM1 is most abundant in thymus, testis, small intestine and colon. Alternative splicing generates FOXM1A and FOXM1B isoforms that contain PEST regions involved in rapid protein degradation. A decrease in FOXM1 expression is associated with age-related defects in cellular proliferation. Conversely, an increase in FOXM1B expression in the livers of older transgenic mice restore hepatocyte DNA replication rates to the higher rate present in young livers. FOXM1B activates the transcription of cyclin B1, cyclin D1 and Cdc25B.

Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

Informations pour la commande

Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

Anticorps FOXM1 (E-10)

sc-376621
200 µg/ml
$316.00

FOXM1 (E-10): m-IgG Fc BP-HRP Kit

sc-540616
200 µg Ab; 10 µg BP
$354.00

FOXM1 (E-10): m-IgG1 BP-HRP Kit

sc-542247
200 µg Ab; 20 µg BP
$354.00

FOXM1 (E-10) peptide neutralisant

sc-376621 P
100 µg/0.5 ml
$68.00

Anticorps FOXM1 (E-10) X

sc-376621 X
200 µg/0.1 ml
$316.00

What application is the blocking peptide sc-376621 P appropriate for?

Posée par: TinTin
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Répondue par: Technical Support
Date de publication: 2017-02-24
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Rated 4 de 5 de par Good specificity in WB in CCRFGood specificity in WB in CCRF-CEM whole cell lysate. -SCBT QC
Date de publication: 2015-03-04
Rated 4 de 5 de par Very robust signal seen in WB in human FOXM1Very robust signal seen in WB in human FOXM1 transfected 293T whole cell lysate. -SCBT QC
Date de publication: 2014-10-29
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Anticorps FOXM1 (E-10) est évalué 4.0 de 5 de 2.
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