
FADD Antibody (H-10) is a mouse monoclonal IgG2a kappa light chain antibody designed to detect the Fas-Associated Death Domain (FADD), also known as GIG3, or MORT1. FADD monoclonal antibody (H-10) targets an epitope spanning amino acids 28-209 at the C-terminus of human FADD, ensuring high specificity and reliable binding. FADD is predominantly localized in the cytoplasm, where FADD plays a crucial role in apoptotic signaling by linking death receptors such as FAS and TNFR1 to downstream caspases, thereby facilitating programmed cell death. This cytoplasmic localization is essential for maintaining cellular homeostasis, regulating immune responses, and preventing uncontrolled cell proliferation, which is vital in cancer and autoimmune disease research. Anti-FADD antibody (H-10) is validated for the detection of human FADD in various applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). By enabling precise investigation of FADD′s cellular functions and interactions, FADD (H-10) antibody serves as an indispensable tool for researchers studying the mechanisms of apoptosis and its implications in health and disease. Anti-FADD antibody (H-10) high affinity and specificity make FADD ideal for elucidating the complex pathways involved in cell death and survival. Whether exploring fundamental biological processes or developing therapeutic strategies, FADD monoclonal antibody (H-10) provides reliable performance and consistent results.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
FADD Antibody (H-10) | sc-271520 | 200 µg/ml | $322.00 |