Date published: 2025-9-9

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Anticorps FADD (H-10): sc-271520

5.0(2)
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Fiches techniques
  • L'Anticorps FADD (H-10) est un monoclonal de souris IgG2a κ, cité dans 7 publications, fourni en 200 µg/ml
  • dirigé contre les acides aminés 28-209 situés au niveau C-terminus de FADD d'origine human
  • recommandé pour la détection de FADD d'origine human par WB, IP, IF et ELISA
  • Voir FADD (G-4): sc-271748 pour d'autres anticorps conjugués FADD, dont AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 et 790.
  • Nous testons actuellement encore nos anticorps secondaires pour trouver la meilleure protéine de liaison pour cet anticorps primaire FADD (H-10). Veuillez nous contacter si vous avez des questions concernant les réactifs de détection secondaire appropriés.

ACCÈS RAPIDE AUX LIENS

VOIR ÉGALEMENT...

In contrast to growth factors which promote cell proliferation, FAS ligand (FAS-L) and the tumor necrosis factors (TNFs) rapidly induce apoptosis. Cellular response to FAS-L and TNF is mediated by structurally related receptors containing a conserved "death domain" and belonging to the TNF receptor superfamily. TRADD, FADD and RIP are FAS/TNF-R1 interacting proteins that contain a death domain homologous region (DDH). TRADD (TNF-R1-associated death domain) and FADD (FAS-associated death domain) associate with the death domains of both FAS and TNF-R1 via their DDH regions. Overexpression of TRADD leads to NFkB activation and apoptosis in the absence of TNF. Overexpression of FADD causes apoptosis, which can be blocked by the cow pox protein CrmA, suggesting that FADD lies upstream of ICE and possibly other serine proteases. The receptor interacting protein, RIP, associates with FAS exclusively via its DDH and this association is abrogated in lpr mutants. Unlike TRADD and FADD, RIP contains a putative amino terminal kinase domain.

Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

Informations pour la commande

Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

Anticorps FADD (H-10)

sc-271520
200 µg/ml
$316.00

What is the recommended starting dilution for Western blot for sc-271520: FADD (H-10) monoclonal antibody?

Posée par: Trav11
The recommended starting dilution for Western blot is 1:100 with a dilution range of 1:100-1:1000. This information, along with other technical specifications, is available in the recommended protocol: https://www.scbt.com/scbt/resources/protocols/western-immuno-blotting
Répondue par: Technical Support
Date de publication: 2017-03-22
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Rated 5 de 5 de par Satisfactory Western Blot data of FADD expressionSatisfactory Western Blot data of FADD expression in SW480, THP-1 and A-431 whole cell lysates. -SCBT QC
Date de publication: 2015-02-10
Rated 5 de 5 de par Produced positive Western Blot data of FADDProduced positive Western Blot data of FADD expression in THP-1 whole cell lysate. -SCBT QC
Date de publication: 2014-01-26
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Anticorps FADD (H-10) est évalué 5.0 de 5 de 2.
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