Anticorps F4/80 (6A545): sc-71085
- L'anticorps F4/80 6A545 est un monoclonal IgG2a de rat, cité dans 16 publications, fourni en 100 µg/ml
- élevé contre des macrophages cultivés dérivés de la moelle osseuse d'origine mouse.
- recommandé pour la détection de EMR1 of human origin, F4/80 of mouse origin and the corresponding rat homolog par WB, IF, IHC(P) et FCM
- Voir F4/80 (C-7): sc-377009 pour d'autres anticorps conjugués F4/80, dont AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 et 790.
- Nous testons actuellement encore nos anticorps secondaires pour trouver la meilleure protéine de liaison pour cet anticorps primaire F4/80 (6A545). Veuillez nous contacter si vous avez des questions concernant les réactifs de détection secondaire appropriés.
The epidermal growth factor (EGF)-TM7 family constitutes a group of class B G-protein coupled receptors, which includes CD97, EMR1 (EGF-like molecule containing mucin-like hormone receptor 1, designated F4/80 in mouse), EMR2, EMR3, FIRE, and ETL. These family members are characterized by an extended extracellular region with several N-terminal EGF domains, and are predominantly expressed on cells of the immune system. The EGF-TM7 protein family are encoded by a gene cluster on human chromosome 19p13. The F4/80 molecule is solely expressed on the surface of macrophages and serves as a marker for mature macrophage tissues, including Kupffer cells in liver, splenic red pulp macrophages, brain microglia, gut lamina propria, and Langerhans cells in the skin. F4/80/EMR1 undergoes extensive N-linked glycosylation as well as some O-linked glycosylation. The function of F4/80/EMR1 is unclear, but it is speculated to be involved in macrophage adhesion events, cell migration, or as a G-protein coupled signaling component of macrophages.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps F4/80 (6A545) | sc-71085 | 100 µg/ml | $316.00 |