Date published: 2025-9-10

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Anticorps eIF3ε (H-4): sc-514292

5.0(1)
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Fiches techniques
  • L'Anticorps eIF3ε (H-4) est un monoclonal de souris IgG2b κ, cité dans 1 publications, fourni en 200 µg/ml
  • dirigé contre les acides aminés 78-229 dans une région interne de eIF3ε d'origine human
  • recommandé pour la détection de eIF3ε d'origine mouse, rat et human par WB, IP, IF, IHC(P) et ELISA
  • m-IgG Fc BP-HRP, m-IgG2b BP-HRP et m-IgGκ BP-HRP sont les réactifs secondaires recommandés pour la détection de l'anticorps eIF3ε (H-4) pour des applications de WB and IHC(P). Ces réactifs sont maintenant proposés en kit avec l'anticorps eIF3ε (H-4) (voir Informations pour la commande ci-dessous).

ACCÈS RAPIDE AUX LIENS

VOIR ÉGALEMENT...

The initiation of protein synthesis in eukaryotic cells is regulated by interactions between protein initiation factors and RNA molecules. Eukaryotic initiation factors (eIFs) are utilized in a sequence of reactions that lead to 80S ribosomal assembly and, ultimately, translation. The eukaryotic initiation factor-3 (eIF3) scaffolding structure is the largest of the eIF complexes and includes eIF3α, eIF3β, eIF3γ, eIF3δ, eIF3ε, eIF3Ω, eIF3η and eIF3θ, all of which function to control the assembly of the 40S ribosomal subunit. Association of eIF3 proteins with the 40S ribosomal subunit stabilizes eIF2-GTP-Met-tRNAiMet complex association and mRNA binding, and promotes dissociation of 80S ribosomes into 40S and 60S subunits, thereby promoting the assembly of the pre-initiation complex. Overexpression of eIF3 proteins is common in several cancers, suggesting a role for eIF3 proteins in tumorigenesis.

Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

Informations pour la commande

Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

Anticorps eIF3ε (H-4)

sc-514292
200 µg/ml
$316.00

eIF3ε (H-4): m-IgG Fc BP-HRP Kit

sc-538617
200 µg Ab; 10 µg BP
$354.00

eIF3ε (H-4): m-IgGκ BP-HRP Kit

sc-536261
200 µg Ab; 40 µg BP
$354.00

eIF3ε (H-4): m-IgG2b BP-HRP Kit

sc-549963
200 µg Ab; 10 µg BP
$354.00

Can eIF3ε (H-4): sc-514292 monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

Posée par: jenniferc
Thank you for your question. Yes, eIF3ε (H-4): sc-514292 has been validated for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Répondue par: Technical Support
Date de publication: 2017-02-27
  • y_2025, m_9, d_9, h_6CST
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Rated 5 de 5 de par Works very well in WesternWorks very well in Western, endogenous detection seen in A-431 and HeLa whole cell lysates -SCBT QC
Date de publication: 2013-07-01
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Anticorps eIF3ε (H-4) est évalué 5.0 de 5 de 1.
  • y_2025, m_9, d_9, h_6
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  • cp_1, bvpage1
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  • CLOUD, getAggregateRating, 117ms
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