Anti-L'anticorps EDG-2 D-6 est un monoclonal IgG2b (chaîne légère kappa) L'Anticorps EDG-2 fourni en 200 µg/ml
spécifique pour un épitope situé entre les acides aminés 190-207 dans un domaine extracellulaire de EDG-2 de human
recommandé pour la détection de EDG-2 d'origine mouse, rat et human par WB, IP, IF, IHC(P) et ELISA
m-IgG Fc BP-HRP, m-IgG2b BP-HRP et m-IgGκ BP-HRP sont les réactifs secondaires recommandés pour la détection de l'anticorps EDG-2 (D-6) pour des applications de WB and IHC(P). Ces réactifs sont maintenant proposés en kit avec l'anticorps EDG-2 (D-6) (voir Informations pour la commande ci-dessous).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
ACCÈS RAPIDE AUX LIENS
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
EDG-2 Antibody (D-6) is a high quality monoclonal EDG-2 antibody (also designated EDG2 antibody, LPAR1 antibody, or LPA1 antibody) suitable for the detection of the EDG-2 protein of mouse, rat and human origin. EDG-2 Antibody (D-6) is available as the non-conjugated anti-EDG-2 antibody. The EDG (endothelial differentiation gene) family of G protein coupled receptors consists of eight family members that bind lysophospholipid (LPL) mediators, including sphingosine-1-phosphate (SPP) and lysophosphatidic acid (LPA). EDG-1, EDG-3, EDG-5 (also designated H218 and AGR16) and EDG-8 bind SPP with high affinity. EDG-6 is a low affinity receptor for SPP. LPA preferentially binds to EDG-2, EDG-4 and EDG-7. The EDG receptors couple to multiple G proteins to signal through Ras, MAP kinase, Rho, Phospholipase C or other tyrosine kinases, which lead to cell survival, growth, migration and differentiation. EDG-1 signals through Gi proteins to activate Akt and is expressed in glioma cells. EDG-2 is expressed in brain, especially in white matter tract regions, while EDG-3 is expressed in cardiovascular tissue and in cerebellum. EDG-4 is highly expressed on leukocytes and brain, and EDG-5 has wide tissue distribution, including cardiovascular tissue and brain. EDG-6, which is expressed in lymphoid and hematopoietic tissues and in lung, signals through G(i/o) proteins, which activate growth related pathways.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.