Molecular structure of Ebastine, CAS Number: 90729-43-4
Ebastine (CAS 90729-43-4)
See product citations (2)
Application:
Ebastine is an antagonist of the histamine H1-receptor
CAS Number:
90729-43-4
Purity:
≥98%
Molecular Weight:
469.66
Molecular Formula:
C32H39NO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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Safety Information
SDS & Certificate of Analysis
Ebastine is a non-sedating histamine H1 receptor antagonist that inhibits T cell migration as well and may find a use in the treatment of Th2-type autoimmune diseases.
Ebastine (CAS 90729-43-4) References
- Cardiac effects of ebastine and other antihistamines in humans. | Moss, AJ. and Morganroth, J. 1999. Drug Saf. 21 Suppl 1: 69-80; discussion 81-7. PMID: 10597870
- Ebastine: an update of its use in allergic disorders. | Hurst, M. and Spencer, CM. 2000. Drugs. 59: 981-1006. PMID: 10804044
- Ebastine inhibits T cell migration, production of Th2-type cytokines and proinflammatory cytokines. | Nori, M., et al. 2003. Clin Exp Allergy. 33: 1544-54. PMID: 14616867
- Ebastine in allergic rhinitis and chronic idiopathic urticaria. | Sastre, J. 2008. Allergy. 63 Suppl 89: 1-20. PMID: 19032340
- A Critical Review of Physicochemical Properties and Analytical Methods Applied to Quantitative Determination of Ebastine. | Frare, RG. and Singh, AK. 2018. Crit Rev Anal Chem. 48: 102-109. PMID: 29235880
- Ebastine in the Treatment of Allergic Rhinitis and Urticaria: 30 Years of Clinical Studies and Real-World Experience. | Sastre, J. 2020. J Investig Allergol Clin Immunol. 30: 156-168. PMID: 30977465
- Ebastine impairs metastatic spread in triple-negative breast cancer by targeting focal adhesion kinase. | Seo, J., et al. 2023. Cell Mol Life Sci. 80: 132. PMID: 37185776
- Repositioning the antihistamine ebastine as an intracellular siRNA delivery enhancer. | Muntean, C., et al. 2023. Int J Pharm. 644: 123348. PMID: 37633539
- Ebastine. a review of its pharmacological properties and clinical efficacy in the treatment of allergic disorders. | Wiseman, LR. and Faulds, D. 1996. Drugs. 51: 260-77. PMID: 8808167
- A preclinical overview of ebastine. Studies on the pharmacological properties of a novel histamine H1 receptor antagonist. | Roberts, DJ. 1996. Drugs. 52 Suppl 1: 8-14. PMID: 8828021
Inhibitor of:
Histamine H1 Receptor.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ebastine, 1 g | sc-205663 | 1 g | $104.00 | |||
Ebastine, 5 g | sc-205663A | 5 g | $420.00 |