DL-Serine (CAS 302-84-1)
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DL-Serine is a non-essential amino acid that plays a role in various biochemical processes. It functions as a building block for proteins and is involved in the synthesis of purines and pyrimidines, which are key components of DNA and RNA. DL-Serine also acts as a precursor for several important metabolites, including glycine, cysteine, and phospholipids. At the molecular level, DL-Serine is involved in the regulation of NMDA receptors in the central nervous system, modulating synaptic transmission and plasticity. It serves as a co-agonist of the NMDA receptor, contributing to the regulation of neuronal excitability and synaptic function. Its mechanism of action involves binding to specific receptor sites and influencing the activity of NMDA receptors, thereby affecting neuronal signaling and synaptic function.
DL-Serine (CAS 302-84-1) References
- A comparative study of enzymatic staining reactions in the rat kidney with necrobiosis induced by ischemia and nephrotoxic agents (mercuhydrin and DL-serine). | WACHSTEIN, M. and MEISEL, E. 1957. J Histochem Cytochem. 5: 204-20. PMID: 13449308
- The formation of glycine and serine; the influence of the administration of glycine, DL-serine and other compounds on levels of tissue glycine and serine. | SIMKIN, JL. and WHITE, K. 1957. Biochem J. 67: 287-91. PMID: 13471548
- Effect of single dose of DL-serine on lipide phosphorylation in kidney of rats. | CORNATZER, WE., et al. 1960. Proc Soc Exp Biol Med. 104: 288-90. PMID: 13811997
- Antagonisms in the utilization of D-amino acids by lactic acid bacteria. II. Influence of DL-serine and glycine on the utilization of D-alanine. | CAMIEN, MN. and DUNN, MS. 1950. J Biol Chem. 185: 553-9. PMID: 14774396
- THE CHANGES IN RAT KIDNEY COCARBOXYLASE ASSOCIATED WITH THE INJURIOUS EFFECTS OF dl-SERINE. | Fishman, WH. and Govier, WM. 1945. Science. 101: 277-9. PMID: 17751183
- The Nephrotoxic Action of DL-Serine as Related to Certain Dietary Factors. | Morehead, RP., et al. 1946. Am J Pathol. 22: 385-93. PMID: 19970870
- Discrimination of chiral solids: a terahertz spectroscopic investigation of L- and DL-serine. | King, MD., et al. 2010. J Phys Chem A. 114: 2945-53. PMID: 20143834
- Influence of dl-methionine and other substances on the nephrotoxic action of dl-serine. | WACHSTEIN, M. 1947. Nature. 159: 236. PMID: 20285663
- The relative toxicity of l- and dl-serine in rats. | ARTOM, C., et al. 1945. Proc Soc Exp Biol Med. 60: 284-7. PMID: 21006318
- Enzymatic production of L-tryptophan from DL-serine and indole by a coupled reaction of tryptophan synthase and amino acid racemase. | Ishiwata, K., et al. 1990. Biotechnol Appl Biochem. 12: 141-9. PMID: 2109982
- Enantioselective synthesis induced by chiral crystal composed of DL-serine in conjunction with asymmetric autocatalysis. | Kawasaki, T., et al. 2011. Org Lett. 13: 2361-3. PMID: 21434610
- Effect of pressure on crystalline L- and DL-serine: revisited by a combined single-crystal X-ray diffraction at a laboratory source and polarized Raman spectroscopy study. | Zakharov, BA., et al. 2012. Acta Crystallogr B. 68: 275-86. PMID: 22610678
- Raman Scattering Study of Amino Acids Adsorbed on a Silver Nanoisland Film. | Skvortsov, A., et al. 2022. Sensors (Basel). 22: PMID: 35891129
- dl-Serine Covalently Ornamented and Ln3+-Incorporated Arsenotungstates with Fast-Responsive Photochromic and Photoinduced Luminescent Switchable Behaviors. | Zheng, K., et al. 2022. Inorg Chem. 61: 15871-15879. PMID: 36174202
- DL-Serine: promoting activity on renal tumorigenesis by N-ethyl-N-hydroxyethylnitrosamine in rats. | Hiasa, Y., et al. 1984. J Natl Cancer Inst. 73: 297-9. PMID: 6429402
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
DL-Serine, 25 g | sc-255133 | 25 g | $20.00 |