Date published: 2025-9-8

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Anticorps Dicer (D-11): sc-136980

5.0(2)
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Fiches techniques
  • L'Anticorps Dicer (D-11) est un monoclonal de souris IgG2a κ, cité dans 4 publications, fourni en 200 µg/ml
  • soulevée contre les acides aminés 1701-1912 correspondant à C-terminus de Dicer d'origine human.
  • recommandé pour la détection de Dicer d'origine mouse, rat et human par WB, IP, IF, IHC(P) et ELISA
  • Voir Dicer (F-10): sc-136979 pour d'autres anticorps conjugués Dicer, dont AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 et 790.
  • m-IgG Fc BP-HRP et m-IgG2a BP-HRP sont les réactifs secondaires recommandés pour la détection de l'anticorps Dicer (D-11) pour des applications de WB and IHC(P). Ces réactifs sont maintenant proposés en kit avec l'anticorps Dicer (D-11) (voir Informations pour la commande ci-dessous).

ACCÈS RAPIDE AUX LIENS

VOIR ÉGALEMENT...

The mammalian Dicer is a type III RNase-related protein with orthologs in yeast, Drosophila and Arabidopsis. Dicer contains an RNA-helicase motif including a DEXH-box in its amino-terminus and an RNase motif in the carboxy-terminus. The gene encoding human Dicer maps to chromosome 14q31. Dicer is expressed in brain, heart, liver, lung, pancreas, kidney and placenta and functions in the RNA interference pathway. Dicer cleaves short hairpin RNA precursors of approximately 70 bp into 21-23 bp dsRNAs that selectively target the destruction of homologous RNAs. Dicer localizes to the cytoplasm of mammalian cells. Specifically, it co-localizes with calreticulin in the endoplasmic reticulum. Although the cleavage of RNA by Dicer is ATP-independent, the product release necessary for the rapid turnover of this enzyme may be attributed to ATP. Immunoprecipitation studies indicate Dicer forms a complex with PIWI domain of eIF2C translation initiation factors.

Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

Informations pour la commande

Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

Anticorps Dicer (D-11)

sc-136980
200 µg/ml
$316.00

Dicer (D-11): m-IgG Fc BP-HRP Kit

sc-539911
200 µg Ab; 10 µg BP
$354.00

Dicer (D-11): m-IgG2a BP-HRP Kit

sc-546817
200 µg Ab; 10 µg BP
$354.00

What volume is the sc-136980?

Posée par: ningo
Thank you for your question. This antibody is supplied as 200 µg in 1 ml PBS with 0.1 % gelatin and <0.1 % sodium azide.
Répondue par: Tech Support Europe
Date de publication: 2022-02-01

I am using Dicer (D-11): sc-136980 monoclonal antibody to stain paraffin embedded tissue. Do you recommend antigen retrieval when using this antibody?

Posée par: AbPolly
We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Répondue par: Technical Support
Date de publication: 2017-02-24
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Rated 5 de 5 de par Satisfactory Western Blot data of human recombinantSatisfactory Western Blot data of human recombinant Dicer enzyme. -SCBT QC
Date de publication: 2015-04-11
Rated 5 de 5 de par Produced positive Western Blot data of DicerProduced positive Western Blot data of Dicer expression in HeLa, Jurkat, U-2 OS and K-562 whole cell lysates. -SCBT QC
Date de publication: 2014-05-11
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Anticorps Dicer (D-11) est évalué 5.0 de 5 de 2.
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