DDX59 Antibody (B-3): sc-514814

DDX59 Antibody (B-3) is a mouse monoclonal IgG1 antibody that detects DDX59 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). DDX59, also known as ZNHIT5, is a 619 amino acid protein belonging to the DEAD box helicase family, which is characterized by the conserved Asp-Glu-Ala-Asp motif and is implicated in critical cellular processes, including RNA secondary structure modifications and the assembly of ribosomes and spliceosomes. DDX59′s function is vital for maintaining proper RNA metabolism, which is essential for gene expression regulation and cellular homeostasis. DDX59 is expressed in two isoforms due to alternative splicing, featuring a helicase C-terminal domain and a HIT-type zinc finger, both of which are crucial for helicase activity and interactions with RNA. The presence of the Q motif within DDX59 plays a significant role in ATP binding and hydrolysis, further underscoring DDX59′s importance in energy-dependent RNA processing events. Anti-DDX59 antibody (B-3) is an invaluable tool for researchers studying the intricate roles of RNA helicases in various biological processes and diseases.

The preferred DDX59 antibody is DDX59 Antibody (C-3): sc-514439.