Molecular structure of Dapoxetine Hydrochloride, CAS Number: 129938-20-1
Dapoxetine Hydrochloride (CAS 129938-20-1)
Application:
Dapoxetine Hydrochloride is a selective serotonin reuptake inhibitor
CAS Number:
129938-20-1
Molecular Weight:
341.87
Molecular Formula:
C21H23NO•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Dapoxetine Hydrochloride is a selective serotonin reuptake inhibitor (SSRI). It works by increasing the levels of serotonin in the brain. Dapoxetine Hydrochloride is a white to off-white powder that is soluble in water and has a molecular formula of C21H23NO•HCl. It is a potent and highly selective inhibitor of serotonin reuptake, with a high affinity for the serotonin transporter. Dapoxetine Hydrochloride has a half-life of approximately 1-2 hours.
Dapoxetine Hydrochloride (CAS 129938-20-1) References
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- The role of dapoxetine hydrochloride on-demand for the treatment of men with premature ejaculation. | De Hong, C., et al. 2014. Sci Rep. 4: 7269. PMID: 25434754
- A novel and practical asymmetric synthesis of dapoxetine hydrochloride. | Zhu, Y., et al. 2015. Beilstein J Org Chem. 11: 2641-5. PMID: 26734109
- Dual-purpose vardenafil hydrochloride/dapoxetine hydrochloride orodispersible tablets: in vitro formulation/evaluation, stability study and in vivo comparative pharmacokinetic study in healthy human subjects. | El-Refai, K., et al. 2018. Drug Dev Ind Pharm. 44: 988-1000. PMID: 29325456
- Capillary electrophoresis method for the determination of (R)-dapoxetine, (3S)-3-(dimethylamino)-3-phenyl-1-propanol, (S)-3-amino-3-phenyl-1-propanol and 1-naphthol as impurities of dapoxetine hydrochloride. | Harnisch, H. and Scriba, GKE. 2019. J Pharm Biomed Anal. 162: 257-263. PMID: 30273816
- Validated spectrophotometric and spectrofluorimetric methods for determination of dapoxetine hydrochloride and dosulepin hydrochloride in their dosage forms using mercurochrome. | Elama, HS., et al. 2018. Luminescence. 33: 1306-1313. PMID: 30378237
- Linear Support Vector Regression and Partial Least-Squares for Determination of Dapoxetine Hydrochloride and Tadalafil in Binary Pharmaceutical Mixtures. | Anwar, BH., et al. 2020. J AOAC Int. 103: 132-139. PMID: 31319900
- Quantitative determination of Dapoxetine Hydrochloride and Tadalafil using different validated spectrophotometric methods. | Magdy, MA., et al. 2020. Spectrochim Acta A Mol Biomol Spectrosc. 226: 117611. PMID: 31606673
- Native and synchronous fluorescence spectroscopy for determination of avanafil in presence of its co-formulated drug (dapoxetine hydrochloride): Application to pharmaceutical product, biological fluid and content uniformity. | Mohamed, TA. and Atty, SA. 2020. Spectrochim Acta A Mol Biomol Spectrosc. 229: 117898. PMID: 31901802
- Enhanced pharmacokinetic performance of dapoxetine hydrochloride via the formulation of instantly-dissolving buccal films with acidic pH modifier and hydrophilic cyclodextrin: Factorial analysis, in vitro and in vivo assessment. | Aldawsari, HM. and Badr-Eldin, SM. 2020. J Adv Res. 24: 281-290. PMID: 32419956
- One-pot micellar augmented native fluorescence for facile fluorimetric assay of dapoxetine hydrochloride in biological plasma and tablets. | Abu-Hassan, AA., et al. 2020. Spectrochim Acta A Mol Biomol Spectrosc. 239: 118512. PMID: 32470817
- Determination of Dapoxetine Hydrochloride in Human Plasma by HPLC-MS/MS and Its Application in a Bioequivalence Study. | Zhang, X., et al. 2022. Molecules. 27: PMID: 35566058
Inhibitor of:
PDE5A.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Dapoxetine Hydrochloride, 10 mg | sc-218076 | 10 mg | $59.00 | |||
Dapoxetine Hydrochloride, 1 g | sc-218076A | 1 g | $265.00 |