In animals, P450 enzymes serve two major functions: biosynthesis of steroids, fatty acids and bile acids; and the metabolism of endogenous and a wide variety of exogenous substrates, such as toxins and drugs. The four major families involved in drug metabolism are CYP 1,2,3, and 4. The hepatic CYP4A enzymes are important fatty acid and prostaglandin omega-hydroxylases that are highly inducible by fibric acid hypolipidemic agents and other peroxisome proliferators. In humans, 4A1, 4A2 and 4A3 have been cloned from liver, kidney and testis and have been detected in renal, hepatic & brain microvessels.
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Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps CYP4A1 (h1) | sc-73580 | 200 µg/ml | $316.00 |