cyclin A Antibody (E70.1): sc-53231
- cyclin A Antibody (E70.1) is a mouse monoclonal IgG2a κ, cited in 1 publications, provided at 200 µg/ml
- raised against bovine cyclin A
- recommended for detection of cyclin A of mouse, rat, human and bovine origin by WB and IP
- See cyclin A (B-8): sc-271682 for cyclin A antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgGκ BP-HRP is the preferred secondary detection reagent for cyclin A Antibody (E70.1) for WB applications. This reagent is now offered in a bundle with cyclin A Antibody (E70.1) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
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Cyclin A Antibody (E70.1) is a mouse monoclonal IgG2a light chain antibody that detects cyclin A in mouse, rat, human, and bovine samples through applications such as western blotting (WB) and immunoprecipitation (IP). Cyclin A plays a pivotal role in the regulation of the eukaryotic cell cycle, particularly during the S phase, where cyclin A is crucial for the proper progression of DNA replication. Cyclin A is primarily located in the nucleus, where cyclin A associates with cyclin-dependent kinase-2 (Cdk2) to form active complexes that drive cell cycle transitions. Nuclear localization of cyclin A is essential for function, as this positioning allows for timely activation of target substrates necessary for cell division. Additionally, cyclin A has been implicated in various cellular processes, including cell transformation, and interacts with key regulatory proteins such as E1A, transcription factors DRTF1 and E2F, and the retinoblastoma protein, p110. Anti-cyclin A antibody (E70.1) is an invaluable tool for researchers studying cell cycle dynamics and the molecular mechanisms underlying cell proliferation and transformation.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
cyclin A Antibody (E70.1) | sc-53231 | 200 µg/ml | $322.00 | |||
cyclin A Antibody (E70.1): m-IgGκ BP-HRP Bundle | sc-520962 | 200 µg Ab, 40 µg BP | $361.00 |