Date published: 2025-9-9

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Anticorps CRF-BP (G-2): sc-365427

5.0(2)
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Fiches techniques
  • L'Anticorps CRF-BP (G-2) est un monoclonal de souris IgM (chaîne légère kappa) fourni en 200 µg/ml
  • spécifique d'un épitope situé entre les acides aminés 299-322 au niveau C-terminus de CRF-BP d'origine human
  • recommandé pour la détection de CRF-BP d'origine human par WB, IP, IF et ELISA
  • Nous testons actuellement encore nos anticorps secondaires pour trouver la meilleure protéine de liaison pour cet anticorps primaire CRF-BP (G-2). Veuillez nous contacter si vous avez des questions concernant les réactifs de détection secondaire appropriés.

    ACCÈS RAPIDE AUX LIENS

    VOIR ÉGALEMENT...

    Response to stress in mammals requires an intact hypothalamic-pituitary-adrenal axis. The proximal part of the response is mediated by secretion of corticotropin-releasing hormone (CRH) by the paraventricular nucleus of the hypothalamus. CRH is a 41 amino acid peptide derived by enzymatic cleavage from a 191 amino acid preprohormone. CRH is produced not only in the hypothalamus but also in peripheral tissues, such as T lymphocytes; it is highly expressed in human placenta. Glucocorticoids stimulate placental CRH synthesis and secretion in primary cultures of human placenta. This stimulation is in contrast to the glucocorticoid suppression of CRH expression in hypothalamus. The gene which encodes CRH maps to human chromosome 8q13. Human plasma contains a CRH-binding protein, CRH-BP (also designated CRF-BP) which inactivates CRH and which may prevent inappropriate pituitary-adrenal stimulation in pregnancy. The gene which encodes CRF-BP maps to human chromosome 5q11.2-q13.3.

    Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

    Informations pour la commande

    Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

    Anticorps CRF-BP (G-2)

    sc-365427
    200 µg/ml
    $316.00

    CRF-BP (G-2) peptide neutralisant

    sc-365427 P
    100 µg/0.5 ml
    $68.00

    What application is the blocking peptide sc-365427 P appropriate for?

    Posée par: AbPolly
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Répondue par: Technical Support
    Date de publication: 2017-03-01
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    Rated 5 de 5 de par Exceptional immunofluorescence cytoplasmicExceptional immunofluorescence cytoplasmic staining in methanol-fixed HeLa cells. -SCBT QC
    Date de publication: 2015-05-18
    Rated 5 de 5 de par Nice Western Blot data of rat recombinant CRFNice Western Blot data of rat recombinant CRF-BP. -SCBT QC
    Date de publication: 2014-03-10
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    Anticorps CRF-BP (G-2) est évalué 5.0 de 5 de 2.
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