Anticorps COX5b (B-2): sc-374417
- L'Anticorps COX5b (B-2) est un monoclonal de souris IgG1 κ, cité dans 8 publications, fourni en 200 µg/ml
- dirigé contre les acides aminés 35-129 situés au niveau C-terminus de COX5b d'origine human
- recommandé pour la détection de COX5b d'origine mouse, rat, human par WB, IP, IF, IHC(P) et ELISA
- m-IgG Fc BP-HRP et 1 BP-HRP">m-IgG1 BP-HRP sont les réactifs de détection secondaire préférés pour COX5b Antibody (B-2) for WB and IHC(P) applications. Ces réactifs sont désormais proposés en lots avec COX5b Antibody (B-2)(voir les informations de commande ci-dessous).
The cytochrome c oxidase (COX) family of proteins function as the final electron donor in the respiratory chain to drive a proton gradient across the inner mitochondrial membrane, ultimately resulting in the production of water. The mammalian COX apoenzyme is a dimer, with each monomer consisting of 13 subunits, some of which are mitochondrial and some of which are nuclear. Found in the inner mitochondrial membrane, COX5 is the heme A-containing chain of the oxidase family that converts one molecule of oxygen and four molecules of hydrogen to two molecules of water. Two isoforms of COX5 exist, COX5a and COX5b. When oxygen levels within the cell are high, transcription of COX5a (the aerobic isoform) is up-regulated as the rate of cellular respiration increases. Conversely, when oxygen levels are low, COX5b (the hypoxic isoform) transcription increases and functions to maximize the turnover rate of the COX apoenzyme.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps COX5b (B-2) | sc-374417 | 200 µg/ml | $316.00 | |||
COX5b (B-2): m-IgG Fc BP-HRP Kit | sc-540450 | 200 µg Ab; 10 µg BP | $354.00 | |||
COX5b (B-2): m-IgG1 BP-HRP Kit | sc-542131 | 200 µg Ab; 20 µg BP | $354.00 |