Cdc16 Antibody (E-4): sc-365636
- Cdc16 Antibody (E-4) is a mouse monoclonal IgG1 κ, cited in 3 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 581-609 near the C-terminus of Cdc16 of human origin
- recommended for detection of Cdc16 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including and equine, bovine and porcine
- m-IgG1 BP-HRP is the preferred secondary detection reagent for Cdc16 Antibody (E-4) for WB and IHC(P) applications. This reagent is now offered in a bundle with Cdc16 Antibody (E-4) (see ordering information below).
Cdc16 Antibody (E-4) is a mouse monoclonal IgG1 antibody that detects Cdc16 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). Cdc16 plays a crucial role in the regulation of the cell cycle, particularly as a component of the anaphase-promoting complex (APC), which is essential for the timely degradation of cyclins, such as cyclin B. This degradation is vital for the transition from metaphase to anaphase during cell division, ensuring that cells do not prematurely enter the next phase of the cycle. The proper functioning of Cdc16 and the APC is critical for maintaining genomic stability, as errors in cell cycle regulation can lead to aneuploidy and contribute to tumorigenesis. Cdc16 interacts with other proteins in the APC, including Cdc27 and Cdc34, to form a complex that ubiquitinates target proteins, marking them for degradation by the proteasome. Anti-Cdc16 antibody (E-4) serves as a valuable tool in research focused on cancer biology and cell cycle regulation.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cdc16 Antibody (E-4) | sc-365636 | 200 µg/ml | $322.00 | |||
Cdc16 Antibody (E-4): m-IgG1 BP-HRP Bundle | sc-542694 | 200 µg Ab; 20 µg BP | $361.00 | |||
Cdc16 (E-4) Neutralizing Peptide | sc-365636 P | 100 µg/0.5 ml | $69.00 |