CD45RC Antibody (C455.1F): sc-52494
- CD45RC Antibody (C455.1F) is a rat monoclonal IgG2a provided at 100 µg/ml
- recommended for detection of CD45RC of mouse origin by WB, IP and FCM
- available conjugated to phycoerythrin for IF, IHC(P) and FCM
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for CD45RC Antibody (C455.1F). This work is in progress.
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CD45RC Antibody (C455.1F) is a rat monoclonal IgG2a antibody that recognizes CD45RC in mouse samples through western blotting (WB), immunoprecipitation (IP), and flow cytometry (FCM). CD45RC, also known as PTPRC, is a transmembrane glycoprotein predominantly expressed in hematopoietic cells, where CD45RC (C455.1F) monoclonal antibody plays a crucial role in immune signaling. CD45RC functions as a phosphotyrosine phosphatase within its conserved intracellular domain, regulating tyrosine phosphorylation events initiated by the T cell receptor (TCR)/CD3 complex. CD45RC modulates signaling pathways activated by Src and Syk family protein tyrosine kinases, such as Lck, Fyn, and ZAP-70. These kinases are critical for T cell activation and subsequent immune responses, making CD45RC essential for proper immune function. Anti-CD45RC antibody (C455.1F) specifically targets the CD45RC isoform, generated through alternative splicing of exons 4, 5, and 6, enabling precise detection in various experimental settings and advancing our understanding of immune cell signaling and function.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD45RC Antibody (C455.1F) | sc-52494 | 100 µg/ml | $322.00 | |||
CD45RC Antibody (C455.1F) PE | sc-52494 PE | 100 tests in 2 ml | $349.00 |