The complement cascade is a multi-protein system that functions to clear pathogens from an infected host. Part of the innate (unchanging) immune system, the complement cascade consists of proteins and inactive zymogens that are present in blood and are stimulated by one of several triggers. Once stimulated, the cascade relays amplified responses throughout the body, ultimately activating the cell-killing membrane attack complex which can insert itself into the cell membrane and cause the cell to lyse. C6 (Complement component C6) is a 934 amino acid secreted protein that plays a role in the complement cascade, specifically functioning as part of the membrane attack complex. Expressed as two transcript variants, C6 contains one EGF-like domain, one LDL-receptor class A domain, one MACPF domain, two Sushi domains and three TSP type-1 domains. C6 deficiency is correlated with a higher risk of bacterial infection, further supporting the importance of C6 in the innate immune system.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps C6 (3G11) | sc-66191 | 200 µg/ml | $316.00 | |||
C6 (3G11): m-IgG Fc BP-HRP Kit | sc-539210 | 200 µg Ab; 10 µg BP | $354.00 | |||
C6 (3G11): m-IgG1 BP-HRP Kit | sc-541328 | 200 µg Ab; 20 µg BP | $354.00 |