The regulation of cell death is important for the immune system to function properly. T and B lymphocytes must be censored during their development so that the body can remove the nonfunctional or self-reactive lymphocytes. Genetically polymorphic cell surface antigen (Bu-1) antigens are type I transmembrane glycoproteins that may have an important role in controlling cell survival and/or adhesion during B cell development. Bu-1 is expressed on B cells as well as on a subset of macrophages. Embryonic spleen and bone marrow cells carry the Bu-1 antigen, marking these tissues as prebursal precursors for B cells. Bu-1 can induce a rapid form of cell death similar to apoptosis. Bu-1a and Bu-1b represent the recessive and dominant allelic products, respectivley, of the Bu-1 gene.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps Bu-1a (5K98) | sc-70447 | 100 µg/ml | $316.00 |