Anticorps Btk (DFW): sc-81736
- L'Anticorps Btk (DFW) est un monoclonal de souris IgG1 (chaîne légère kappa) fourni en 200 µg/ml
- élevé contre une protéine recombinante correspondant aux acides aminés 212-275 (domaine SH3) de Btk d'origine human.
- recommandé pour la détection de Btk d'origine mouse, rat et human par WB, IP et FCM
- Voir Btk (E-9): sc-28387 pour d'autres anticorps conjugués Btk, dont AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 et 790.
- m-IgG Fc BP-HRP et 1 BP-HRP">m-IgG1 BP-HRP sont les réactifs de détection secondaire préférés pour Btk Antibody (DFW) for WB applications. Ces réactifs sont désormais proposés en lots avec Btk Antibody (DFW)(voir les informations de commande ci-dessous).
ACCÈS RAPIDE AUX LIENS
VOIR ÉGALEMENT...
The Tec family of non-receptor tyrosine kinases is composed of six proteins designated Tec, Emt (also known as Itk or Tsk), Btk (previously known as Atk, BPK or Emb), Bmx, Txk (also known as Rlk) and Dsrc28C. All members of the family contain SH3 and SH2 domains and, with the exception of Txk and Dsrc28C, also contain a pleckstrin homology (PH) and a Tec homology (TH) domain in their amino termini. Four alternatively spliced forms of Tec are found to be expressed broadly in cells of hematopoietic lineage and hepatocytes. The Emt gene product associates with CD28 and becomes activated subsequent to CD28 ligation. Btk is necessary for proper B cell development, and mutations in the gene encoding Btk have been associated with families suffering from X-linked agammaglobulinemia, also referred to as Bruton's disease. The Bmx protein shares a high degree of homology with Btk and seems to be expressed at highest levels in the heart. Txk expression is T cell-specific, while expression of the Drosophila Tec homolog, Dsrc28C, is developmentally regulated.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps Btk (DFW) | sc-81736 | 200 µg/ml | $316.00 | |||
Btk (DFW): m-IgG Fc BP-HRP Kit | sc-539661 | 200 µg Ab; 10 µg BP | $354.00 | |||
Btk (DFW): m-IgG1 BP-HRP Kit | sc-541642 | 200 µg Ab; 20 µg BP | $354.00 |