Anticorps Brn-2/BRN2/POU3F2 (ZD-12): sc-81981
- L'Anticorps Brn-2/BRN2/POU3F2 (ZD-12) est un monoclonal de souris IgG2b (chaîne légère kappa) fourni en 100 µg/ml
- dirigé contre la Brn-2 recombinante d'origine human
- recommandé pour la détection de precursor and mature Brn-2 d'origine mouse, rat et human par WB, IP et ELISA
- Voir Brn-2/BRN2/POU3F2 (B-2): sc-393324 pour d'autres anticorps conjugués Brn-2/BRN2/POU3F2, dont AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 et 790.
- Nous testons actuellement encore nos anticorps secondaires pour trouver la meilleure protéine de liaison pour cet anticorps primaire Brn-2/BRN2/POU3F2 (ZD-12). Veuillez nous contacter si vous avez des questions concernant les réactifs de détection secondaire appropriés.
The Brn family of transcription factors are found in a highly restricted subset of neurons and are critical to the early embryonic development of the central nervous system. Brn-1 and Brn-2 are class III POU domain proteins. Expressed during the development of the forebrain and coexpressed in most layer II-V cortical neurons, Brn-1 and Brn-2 appear to critically control the initiation of radial migration of cortical neurons. Brn-2 is thought to be involved in smooth muscle cell development and differentiation. Brn-3 is a class IV POU domain protein. Three Brn-3 proteins have been described and are designated Brn-3a, Brn-3b and Brn-3c. Brn-3a has two functional transactivating domains, one at the amino terminus and one at the carboxy terminus. While Brn-3a and Brn-3c stimulate transcription, Brn-3b generally functions as a transcriptional repressor. However, Brn-3b, but not Brn-3a, has been shown to regulate the expression of the acetylcholine receptor.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps Brn-2/BRN2/POU3F2 (ZD-12) | sc-81981 | 100 µg/ml | $333.00 |