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Inhibitor of apoptosis proteins (IAP) are a family of proteins that have baculovirus IAP repeat (BIR) domains and inhibits apoptosis. Apollon (also known as BRUCE or baculoviral IAP repeat-containing protein 6 (BIRC6)) is a large protein that binds to, ubiquitinates and facilitates proteasomal degradation of second mitochondria-derived activator of caspase (Smac) and caspase-9. Apollon can be associated with the membrane of the Golgi system and is expressed in brain cancer cells. Apollon may play a role in tumorigenesis and drug resistance of some brain cancer cell lines.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps Apollon (4) | sc-136214 | 50 µg/0.5 ml | $316.00 |