ACCÈS RAPIDE AUX LIENS
Transient receptor potential ion channels (TRPCs) are a superfamily of six transmembrane segment-spanning, gated cation channels. TRPC subtypes mediate store-operated Ca2+ entry, a process involving Ca2+ influx and replenishment of Ca2+ stores formerly emptied through the action of inositol 1,4,5-trisphospate production and other Ca2+ mobilizing agents. TRP ion channels influence calcium-depletion induced calcium influx processes in response to chemo-, mechano- and osmoregulatory events. ANKTM1, also designated TRPA1, plays a role in both nociceptor and hair cell transduction. Activation of ANKTM1 occurs by perception of noxious cold (< 17° C), and pungent natural compounds, such as garlic, cinnamon oil and mustard oil. Inhibition of ANKTM1 impairs hair cell mechanotransduction. Blocking ANKTM1 may be a therapeutic target for treating cold hyperalgesia caused by inflammation and nerve damage.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps ANKTM1 (C-4) | sc-166469 | 200 µg/ml | $316.00 | |||
ANKTM1 (C-4): m-IgG1 BP-HRP Kit | sc-542663 | 200 µg Ab; 20 µg BP | $354.00 | |||
ANKTM1 (C-4) peptide neutralisant | sc-166469 P | 100 µg/0.5 ml | $68.00 |