α2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include three highly homologous subtypes: α2A, α2B, and α2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. αB-adrenergic receptors (a2B-AR) couple to Gi-protein and induce salt-dependent hypertension in response to catecho-lamines. The carboxy-terminal cytoplasmic domain of a2B-AR can associate with proteins, including the guanine nucleotide exchange factor eIF-2B. α2B-AR transcripts are abundant in rat liver and kidney.
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Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps α2B-AR (C-4) | sc-390429 | 200 µg/ml | $316.00 | |||
α2B-AR (C-4): m-IgG2a BP-HRP Kit | sc-546072 | 200 µg Ab; 10 µg BP | $354.00 |