3-Phenanthrol (CAS 605-87-8)
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3-Phenanthrol is a metabolite derived from Phenanthrene. It falls under the category of organic compounds called phenanthrols, characterized by a phenanthrene (or its hydrogenated form) structure with an attached hydroxyl group. Known alternatively as 3-Hydroxyphenanthrene or 3-phenanthrenol, this molecule is essentially insoluble in water and displays a relatively neutral chemical nature. It is primarily detected in urine and is predominantly found within cell membranes, as indicated by its predicted logP value. The synthesis pathway for 3-Phenanthrol involves a series of chemical reactions starting from readily available starting materials. Key steps in the synthesis include the creation of a benzene ring, followed by a cyclization process to establish the phenanthrene ring system. Subsequently, functionalization of the phenanthrene ring occurs, introducing the hydroxyl group at the 3-position.
3-Phenanthrol (CAS 605-87-8) References
- 1,2-Dimethylimidazole-4-sulfonyl chloride, a novel derivatization reagent for the analysis of phenolic compounds by liquid chromatography electrospray tandem mass spectrometry: application to 1-hydroxypyrene in human urine. | Xu, L. and Spink, DC. 2007. J Chromatogr B Analyt Technol Biomed Life Sci. 855: 159-65. PMID: 17524972
- Metabolism of phenanthrene by Phanerochaete chrysosporium. | Sutherland, JB., et al. 1991. Appl Environ Microbiol. 57: 3310-6. PMID: 1781688
- [Using HPLC-MS/MS method to analyze monohydroxy metabolites of PAHs in urine]. | Huang, C., et al. 2010. Wei Sheng Yan Jiu. 39: 355-7, 360. PMID: 20568469
- Genome-to-function characterization of novel fungal P450 monooxygenases oxidizing polycyclic aromatic hydrocarbons (PAHs). | Syed, K., et al. 2010. Biochem Biophys Res Commun. 399: 492-7. PMID: 20674550
- A fungal P450 (CYP5136A3) capable of oxidizing polycyclic aromatic hydrocarbons and endocrine disrupting alkylphenols: role of Trp(129) and Leu(324). | Syed, K., et al. 2011. PLoS One. 6: e28286. PMID: 22164262
- Regiospecific oxidation of polycyclic aromatic phenols to quinones by hypervalent iodine reagents. | Wu, A., et al. 2010. Tetrahedron. 66: 2111-2118. PMID: 24014894
- [Polycyclic aromatic hydrocarbons monohydroxy metabolites level in urine of general population in eight provinces of China]. | Huang, C., et al. 2014. Zhonghua Yu Fang Yi Xue Za Zhi. 48: 102-8. PMID: 24746003
- An oleaginous endophyte Bacillus subtilis HB1310 isolated from thin-shelled walnut and its utilization of cotton stalk hydrolysate for lipid production. | Zhang, Q., et al. 2014. Biotechnol Biofuels. 7: 152. PMID: 25342975
- Quantification of monohydroxylated polycyclic aromatic hydrocarbons in human urine samples using solid-phase microextraction coupled with glass-capillary nanoelectrospray ionization mass spectrometry. | Yang, BC., et al. 2017. Anal Chim Acta. 973: 68-74. PMID: 28502429
- Propagation Failure by TRPM4 Overexpression. | Gaur, N., et al. 2019. Biophys J. 116: 469-476. PMID: 30598284
- Evaluation of Interventions to Reduce Firefighter Exposures. | Burgess, JL., et al. 2020. J Occup Environ Med. 62: 279-288. PMID: 31977921
- Evaluation of fireground exposures using urinary PAH metabolites. | Hoppe-Jones, C., et al. 2021. J Expo Sci Environ Epidemiol. 31: 913-922. PMID: 33654270
- The effect of alkyl substitution on the oxidative metabolism and mutagenicity of phenanthrene. | Wang, D., et al. 2022. Arch Toxicol. 96: 1109-1131. PMID: 35182162
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
3-Phenanthrol, 2.5 mg | sc-209674 | 2.5 mg | $455.00 | |||
3-Phenanthrol, 5 mg | sc-209674A | 5 mg | $922.00 | |||
3-Phenanthrol, 10 mg | sc-209674B | 10 mg | $1587.00 | |||
3-Phenanthrol, 25 mg | sc-209674C | 25 mg | $3023.00 |