![3-{1-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-1H-indol-3-yl}acrylic acid - chemical structure image](https://media.scbt.com/product/3-1-3-chloro-5-trifluoromethyl-2-pyridinyl-1h-indol-3-ylacrylic-acid-structure_33_57_b_335738.jpg)
![3-{1-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-1H-indol-3-yl}acrylic acid - chemical structure image](https://media.scbt.com/product/3-1-3-chloro-5-trifluoromethyl-2-pyridinyl-1h-indol-3-ylacrylic-acid-structure_33_57_t_335738.jpg "Molecular structure of 3-{1-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-1H-indol-3-yl}acrylic acid")
Molecular structure of 3-{1-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-1H-indol-3-yl}acrylic acid
3-{1-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-1H-indol-3-yl}acrylic acid
Molecular Weight:
366.72
Molecular Formula:
C17H10ClF3N2O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Nigericin sodium salt, a polyether antibiotic K+ and Na+ ionophore, stimulates Ca2+ release from mitochondrial stores by disruption of membrane potential and stimulates ATPase activity leading to rapid intracellular acidification resulting in apoptosis. Nigericin•Na has shown a role for inducing caspase-1-independent necrotic cell death. Nigericin•Na has also been found to increase membrane potential accelerating the rate of superoxide generation approaching the rate obtained by antimycin. Nigericin•Na is an activator of Cryopyrin.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
3-{1-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-1H-indol-3-yl}acrylic acid, 500 mg | sc-312225 | 500 mg | $592.00 | |||
3-{1-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-1H-indol-3-yl}acrylic acid, 1 g | sc-312225A | 1 g | $807.00 |